Behavioral activation and inhibition systems and the severity and course of depression
Behavioral activation and inhibition systems and the severity and course of depression
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DOI：
10.1037//0021-843x.111.4.589
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发表时间：
2002-11-01
影响因子：
4.6
通讯作者：
Gotlib, IH
中科院分区：
文献类型：
--
作者：
Kasch, KL;Rottenberg, J;Gotlib, IH
理论家提出抑郁症与行为激活（BAS）和行为抑制（BIS）系统的异常有关。特别是，抑郁症的人被假设表现出不足的BAS和过度活跃的BIS功能。在62名抑郁症患者和27名非抑郁症对照者中检查了自我报告的BAS和BIS水平。临床功能在入院时和8个月随访时进行评估。相对于非抑郁的控制，抑郁的参与者报告低BAS水平和较高的BIS水平。在抑郁组中，较低的BAS水平与更大的并发抑郁严重程度相关，并预测更差的8个月结局。BIS和BAS水平随时间和临床状态显示相当稳定。总体而言，结果表明，BAS失调加重抑郁症的表现和过程。
Theorists have proposed that depression is associated with abnormalities in the behavioral activation (BAS) and behavioral inhibition (BIS) systems. In particular, depressed individuals are hypothesized to exhibit deficient BAS and overactive BIS functioning. Self-reported levels of BAS and BIS were examined in 62 depressed participants and 27 nondepressed controls. Clinical functioning was assessed at intake and at 8-month follow-up. Relative to nondepressed controls, depressed participants reported lower BAS levels and higher BIS levels. Within the depressed group, lower BAS levels were associated with greater concurrent depression severity and predicted worse-8-month outcome. Levels of both BIS and BAS showed considerable stability over time and clinical state. Overall, results suggest that BAS dysregulation exacerbates the presentation and course of depressive illness.