MORPHOLOGY ENGINEERING OF ORGANIC-CRYSTALS WITH THE ASSISTANCE OF TAILOR-MADE GROWTH-INHIBITORS
MORPHOLOGY ENGINEERING OF ORGANIC-CRYSTALS WITH THE ASSISTANCE OF TAILOR-MADE GROWTH-INHIBITORS
复制标题
DOI：
10.1080/00268948308074685
复制
发表时间：
1983-01-01
影响因子：
0.7
通讯作者：
LEISEROWITZ, L
中科院分区：
文献类型：
--
作者：
ADDADI, L;YELLIN, Z;LEISEROWITZ, L
从晶体结构和添加剂的立体化学角度研究了添加剂对有机晶体生长的阻滞作用。在受影响的生长方向和添加剂的结构之间建立了简单的相关性。这种机制已成功地应用于监测，在一个控制的方式，有机晶体的形态，这是说明苯甲酰胺和苯甲酸。此外，极性晶体和手性分子的绝对构型已被直接指定。这是说明的极性晶体的tr-cinnamoyl丙氨酸，并为苏氨酸的分子，通过形态变化，该分子诱导的中心对称晶体的丝氨酸。
Retardation of growth of organic crystals in the presence of additives in solution has been investigated in terms of their crystal structures and the stereochemistry of the additives. A simple correlation has been established between affected directions of growth and structure of the additive. This mecnanism has been successfully applied for monitoring, in a controlled manner, the morphology of organic crystals; this is illustrated for benzamides and benzoic acids. Furthermore, the absolute configuration of polar crystals and chiral molecules has been directly assigned. This is illustrated for the polar crystal of tr-cinnamoyl alanine, and for the molecule of threonine, through morphological changes this molecule induces in the centrosymmetric crystal of serine.