Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.
Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.
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DOI：
10.1128/mra.01146-19
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发表时间：
2021-03-25
影响因子：
0.8
通讯作者：
Szpara ML
中科院分区：
文献类型：
--
作者：
Renner DW;Parsons L;Shreve JT;Engel EA;Kuny CV;Enquist L;Neumann D;Mangold C;Szpara ML
单纯疱疹病毒1型（HSV-1）菌株McKrae于1965年分离，并已被许多实验室使用。三个HSV-1株McKrae库存先前已经测序，揭示了关键基因的差异。我们对来自James Hill的HSV-1菌株McKrae的基因组进行了测序，以更好地了解分离株之间的遗传差异。单纯疱疹病毒1型（HSV-1）菌株McKrae于1965年分离，并已被许多实验室使用。三个HSV-1株McKrae库存先前已经测序，揭示了关键基因的差异。我们测定了来自James M.希尔，以更好地了解分离株之间的遗传差异。
Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from James Hill, to better understand the genetic differences between isolates. Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.