Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates.

Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates.
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DOI:
10.1016/j.bmcl.2014.03.008
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发表时间:
2014-05
影响因子:
2.7
通讯作者:
Shubhanjan Mitra;S. Mukherjee;S. Sen;A. Hajra
Shubhanjan Mitra;S. Mukherjee;S. Sen;A. Hajra
中科院分区:
医学4区
文献类型:
--
作者:
Shubhanjan Mitra;S. Mukherjee;S. Sen;A. Hajra

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在这项工作中,我们报告了一个环境友好的锌介导的合成芳基和苄基磷酸chlorogenoates在乙醇中在短的反应时间。进行了体外抗菌研究沿着统计分析和种子发芽试验。这些硫族磷酸盐对参比菌株具有很强的抗微生物活性。对枯草杆菌、金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌4种标准菌株进行抗菌活性测定。对一株白色念珠菌进行了抗真菌活性评价。
We report in this work an environmentally benign zinc mediated synthesis of aryl and benzyl phosphorochalcogenoates in ethanol within a short reaction time. In vitro antimicrobial study along with statistical analysis and seed germination assay were performed. These chalcogenophosphates possess strong antimicrobial activity against the reference strains. The antibacterial activity was determined against four standard strains (Bacilus subtilis, Staphylococcus aureus,Escherichia coli, Pseudomonas aeruginosa). The antifungal activity was evaluated against one fungal strain Candida albicans.