Central venous and mixed venous oxygen saturation in critically ill patients
Central venous and mixed venous oxygen saturation in critically ill patients
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DOI：
10.1159/000050511
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发表时间：
2001-05-01
期刊：
影响因子：
3.7
通讯作者：
Baltopoulos, G
中科院分区：
文献类型：
--
作者：
Ladakis, C;Myrianthefs, P;Baltopoulos, G
背景：虽然混合静脉 O-2 饱和度 (SvO(2)) 准确地指示 O-2 供需平衡并提供组织氧合指数，但使用肺动脉 (PA) 导管会带来巨大的成本、风险和并发症。以风险和成本较低的方式获得的中心静脉 O-2 饱和度 (ScvO(2)) 可能是 SvO(2) 的有吸引力的替代方案。目的：探讨 ScvO(2) 和 SvO(2) 值在评估重症 ICU 患者时是否具有良好的相关性和互换性，并创建一个可以根据 ScvO(2) 估计 SvO(2) 的方程。方法：61例机械通气患者入院时插管，同时测量上腔静脉下段和PA的ScvO(2)和SvO(2)值。结果：SvO(2) 为 68.6 +/- 1.2%（平均值 +/- SEM），ScvO(2) 为 69.4 +/- 1.1%。差异具有统计学意义（p < 0.03）。总人群的相关系数 r 为 0.945，手术患者和内科患者的相关系数分别为 0.937 和 0.950。在 90.2% 的患者中，差异是
Background: Although mixed venous O-2 saturation (SvO(2)) accurately indicates the balance of O-2 supply/demand and provides an index of tissue oxygenation, the use of a pulmonary artery (PA) catheter is associated with significant costs, risks and complications. Central venous O-2 saturation (ScvO(2)), obtained in a less risky and costly manner, can be an attractive alternative to SvO(2). Objectives: To investigate whether the values of ScvO(2) and SvO(2) are well correlated and interchangeable in the evaluation of critically ill ICU patients and to create an equation that could estimate SvO(2) from ScvO(2). Methods: Sixty-one mechanically ventilated patients were catheterized upon admission and ScvO(2) and SvO(2) values were simultaneously measured in the lower part of the superior vena cava and PA respectively. Results: SvO(2) was 68.6 +/- 1.2% (mean +/- SEM) and ScvO(2) was 69.4 +/- 1.1%. The difference is statistically significant (p < 0.03). The correlation coefficient r is 0.945 for the total population, 0.937 and 0.950 in surgical and medical patients, respectively. In 90.2% of patients the difference was