Experiment on Hemostasis for Wounds with Collagen Sponge
Experiment on Hemostasis for Wounds with Collagen Sponge
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发表时间：
2002
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通讯作者：
Wu Ji-min
中科院分区：
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作者：
Wu Ji-min
目的研究不同类型胶原海绵对出血创面的止血效果。方法从牛肌腱中提取可溶性胶原，冻干制成海绵状止血材料。采用SDS-PAGE电泳分析胶原海绵的成分。结果以Ⅰ型胶原为主要成分的胶原海绵具有缩短止血时间、减少出血、促进创面愈合的作用。结论胶原海绵是一种良好的止血材料。它可以用作治疗伤口的敷料。
Objective The different types of collagen sponge and their effect on bleeding wounds were studied. Methods The soluble collagen was extracted from bovine tendon and lyophilized to become a spongy hemostatic material. The constituents of collagen sponge were analyzed by SDS-PAGE electrophoresis. The hemostatic effect of different types of collagen sponge was studied on the sterile and infected wounds in rabbit.Results It was demonstrated that the collagen sponge composed of type Ⅰ collagen possessed of the effectiveness in shortening hemostatic duration, reducing bleeding and improving wound cure. Conclusion Collagen sponge is a good hemostatic material. It can be used as tampon for treatment of wounds.