Does Infertility Treatment Increase Male Reproductive Tract Disorder?
Does Infertility Treatment Increase Male Reproductive Tract Disorder?
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DOI：
10.1016/j.urology.2012.12.003
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发表时间：
2013-03-01
期刊：
影响因子：
2.1
通讯作者：
Song, Seung-Hun
中科院分区：
文献类型：
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作者：
Bang, Jeong Kyoon;Lyu, Sang Woo;Song, Seung-Hun
目的 探讨人类辅助生殖技术与婴儿男性生殖障碍的关系。 材料与方法 2008年1月至2011年12月，我院新生儿15332例。我们评估了 7752 名男婴的出生体重、胎龄和其他特征，并确定了受孕方法与婴儿男性生殖障碍之间的关联。我们还分析了男性因素对这些疾病发生的影响。结果99例新生儿（1.3%）被诊断为隐睾症，8例（0.1%）被诊断为尿道下裂，4例（0.05%）被诊断为两者。隐睾在通过体外受精 (IVF) 和 IVF/胞浆内单精子注射 (IVF/ICSI；P
OBJECTIVE To determine the association between assisted human reproduction and male reproductive disorders in infants conceived by this means.MATERIALS AND METHODS Between January 2008 and December 2011, 15,332 neonates were born in our hospital. We assessed the birth weight, gestational age, and other characteristics of the 7752 male infants and determined the association between methods of conception and male reproductive disorders in the infants. We also analyzed the influence of male factor on the occurrence of these disorders.RESULTS Ninety-nine newborns (1.3%) were diagnosed with cryptorchidism, 8 (0.1%) were diagnosed with hypospadias, and 4 (0.05%) were diagnosed with both. Cryptorchidism was more common in children conceived through in vitro fertilization (IVF) and IVF/intracytoplasmic sperm injection (IVF/ICSI; P