The depletion attraction: an underappreciated force driving cellular organization.
The depletion attraction: an underappreciated force driving cellular organization.
复制标题
耗尽吸引力：驱动细胞组织不足的力量。
DOI：
10.1083/jcb.200609066
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发表时间：
2006-12-04
影响因子：
7.8
通讯作者：
Cook, Peter R
中科院分区：
文献类型：
--
作者：
Marenduzzo, Davide;Finan, Kieran;Cook, Peter R
细胞结构是由氢键和离子键加上范德华力和疏水力塑造的。在充满大分子的细胞中，一种鲜为人知的独特力量--“耗竭引力”--也在起作用。我们回顾了这种力量有助于组装从细胞骨架到染色质环和整个染色体的广泛细胞结构的证据。
Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force—the “depletion attraction”—also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes.