Phosphine-catalyzed Friedel-Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

Phosphine-catalyzed Friedel-Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes
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膦催化萘酚与对醌甲基化物的弗里德尔-克来福特反应:快速获得三芳基甲烷

DOI:
10.1039/c7ob00911a
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发表时间:
2017
影响因子:
3.2
通讯作者:
Zhang Junliang
Zhang Junliang
中科院分区:
化学3区
文献类型:
--
作者:
Zhou Tao;Li Shenhuan;Huang Ben;Li Cao;Zhao Yang;Chen Jieqiong;Chen Aoling;Xiao Yuanjin;Liu Lu;Zhang Junliang

文献摘要

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我们开发了一种新型的膦催化萘酚与对醌甲基化物 (p-QM) 的弗里德尔-克来福特反应。该反应为三芳基甲烷的合成提供了一种有前途的方法,三芳基甲烷广泛存在于天然产物和已被证明具有生物和药理活性的分子中。
We developed a novel phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides (p-QMs). This reaction provided a promising method for the synthesis of triarylmethanes, which widely exist in natural products and in molecules which have been shown to have biological and pharmacological activity.