Benign clinical significance of J-wave pattern (early repolarization) in highly trained athletes

Benign clinical significance of J-wave pattern (early repolarization) in highly trained athletes
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DOI:
10.1016/j.hrthm.2014.07.042
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发表时间:
2014-11-01
期刊:
影响因子:
5.5
通讯作者:
Maron, Barry J.
Maron, Barry J.
中科院分区:
医学2区
文献类型:
--
作者:
Quattrini, Filippo M.;Pelliccia, Antonio;Maron, Barry J.

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背景 在没有心血管 (CV) 疾病的情况下,12 导联 ECG 3 波/QRS 模糊(早期复极)与室颤风险增加相关。 目的 本研究的目的是评估大量竞技运动员中 3 波/QRS 模糊的患病率和临床意义。 方法 704 名运动员(436 名男性 [62%],年龄 25 +/- 5 岁)对从事过30种不同运动的人进行了心血管疾病检查。在 1 至 18 年的随访(平均 6 +/- 4 年)内可进行系列临床、心电图和超声心动图评估。 结果 在 102 名运动员 (14 /e) 中发现 J 波,并与 32 名运动员 (4%) 的 QRS 模糊相关。最常见于前导联、侧导联和下导联 (n = 73 [72%]),偶尔见于侧导联 (n = 26 [25%]),很少见于下导联 (n = 3 [3%])。 102 名运动员中的大多数 (n = 86 [84%]) 也表现出 ST 段抬高。 J 波/QRS 模糊与其他训练相关心电图变化(即 76% 的 R/S 波电压增加)和左心室 (LV) 形态重塑(LV 质量 199 +/- 48 g vs 188 +/- 56 g,P
BACKGROUND 3 wave/QRS slurring (early repolarization) on 12-lead ECG has been associated with increased risk for ventricular fibrillation in the absence of cardiovascular (CV) disease.OBJECTIVE The purpose of this study was to assess the prevalence and clinical significance of 3 wave/QRS slurring in a large population of competitive athletes.METHODS Seven hundred four athletes (436 males [62%], age 25 +/- 5 years) free of CV disease who had engaged in 30 different sports were examined. Serial clinical, ECG, and echocardiographic evaluations were available over 1 to 18 years of follow-up (mean 6 +/- 4 years).RESULTS J wave was found in 102 athletes (14 /e) and was associated with QRS slurring in 32 (4%). It was found most commonly in anterior, lateral, and inferior Leads (n = 73 [72%]), occasionally in lateral leads (n = 26 [25%]), and rarely in inferior leads (n = 3 [3%]). Most of 102 athletes (n = 86 [84%]) also showed ST-segment elevation. J wave/QRS slurring was associated with other training-related ECG changes (ie, increased R/S-wave voltages in 76%) and left ventricular (LV) morphologic remodeling (LV mass 199 +/- 48 g vs 188 +/- 56 g, P