NUCLEOTIDE-SEQUENCES OF HS-ALPHA SATELLITE DNA FROM KANGAROO RAT DIPODOMYS-ORDII AND CHARACTERIZATION OF SIMILAR SEQUENCES IN OTHER RODENTS
NUCLEOTIDE-SEQUENCES OF HS-ALPHA SATELLITE DNA FROM KANGAROO RAT DIPODOMYS-ORDII AND CHARACTERIZATION OF SIMILAR SEQUENCES IN OTHER RODENTS
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DOI：
10.1016/0092-8674(77)90170-2
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发表时间：
1977-01-01
期刊：
影响因子：
64.5
通讯作者：
SALSER, W
中科院分区：
文献类型：
--
作者：
FRY, K;SALSER, W
高度重复的卫星HS[重链]-α最常见的重复核苷酸序列。用核糖替代法测定了袋鼠体内奥氏丝虫的组分。该序列长6个核苷酸，约占HS-α总序列的25%。卫星DNA，其余DNA由与最常见的序列相关的序列变体组成。报告了这些变异体中最常见的变种的序列。最常见的重复序列与报道的α相同。豚鼠CAVIA Porcellus的卫星。阿尔法。波塞卢斯、袋鼠和羚羊地鼠的卫星与袋鼠的序列有共同之处。这意味着，哺乳动物卫星DNA最简单的重复序列可能会持续比之前认为的更长的进化时间。试图解释其序列高度保守的卫星的快速数量变化，使我们考虑它们可能在共域物种形成中发挥作用。提出的模型的新特征之一是卫星的波动可能是物种形成基因造成的。这样的基因在某些情况下会赋予很强的选择优势，并可以解释在很短的进化跨度内出现大量新的相关物种的许多令人费解的例子。
The most common repeated nucleotide sequences of the highly repetitive satellite HS[heavy strand]-.alpha. fraction from kangaroo rat D. ordii was determined using ribosubstitution methods. This sequence was 6 nucleotides long and represented about 25% of the total HS-.alpha. satellite DNA, while the remaining DNA was composed of sequence variants related to the most common sequence. The sequences of the commonest of these variants are reported. The most common repeated sequence was identical to that reported for the .alpha. satellite of guinea pig Cavia porcellus. The .alpha. satellites of C. porcellus, pocket gopher Thomomys bottae and the antelope ground squirrel Ammospermophilus leucurus, have sequences in common with the kangaroo rat. This implies that the simplest repeated sequences of mammalian satellite DNA may persist over much longer evolutionary times than previously thought. Attempts to explain the very rapid quantitative changes in satellites whose sequence is strongly conserved have led us to consider that they might have a role in sympatric speciation. Among the novel features of the model presented is that fluctuations in satellites could be due to speciation genes. Such genes would confer a strong selective advantage in certain situations, and could explain the many puzzling instances in which large numbers of new related species have appeared over a short evolutionary span.