Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis.
Modulations in the oscillatory activity of the Globus Pallidus internus neurons during a behavioral task-A point process analysis.
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DOI：
10.1109/iembs.2011.6091037
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Sarma SV
中科院分区：
文献类型：
--
作者：
Saxena S;Gale JT;Eskandar EN;Sarma SV
假设受试者的行为状态反映在某些神经元组的尖峰活动的振荡调制中。特别是，β-和γ-波段已被实验证明与运动皮层和基底神经节部分的运动有关。在这里，我们分析了定向调谐和振荡的β-和γ-波段的神经元在苍白球内（GPi）的两个健康的非人类灵长类动物在径向中心的运动任务之间的关系。我们发现，在运动的规划阶段，显示伽马振荡的定向调谐神经元的百分比相比，显示β振荡的定向调谐神经元的百分比增加。在非定向调谐神经元中没有看到类似的趋势。这表明，参与运动规划的GPi神经元使用伽马波段的振荡来传达信息。
The behavioral state of a subject is hypothesized to be reflected in the oscillatory modulations of the spiking activity of certain groups of neurons. In particular, the beta- and gamma-bands have been experimentally shown to be related to movement in the motor cortex and parts of the basal ganglia. Here, we analyze the relationship between directional tuning and oscillations in the beta- and gamma-bands of the neurons in the Globus Pallidus internus (GPi) of two healthy nonhuman primates during a radial center-out motor task. We find that, during the planning stages of the movement, the percentage of directionally tuned neurons displaying gamma oscillations increases when compared to the percentage of directionally tuned neurons displaying beta oscillations. A similar trend is not seen in non-directionally tuned neurons. This suggests that the GPi neurons involved in the planning of movement communicate information using an emergence of oscillations in the gamma-band.