A REACTION-DIFFUSION WAVE ON THE SKIN OF THE MARINE ANGELFISH POMACANTHUS
A REACTION-DIFFUSION WAVE ON THE SKIN OF THE MARINE ANGELFISH POMACANTHUS
复制标题
DOI：
10.1038/376765a0
复制
发表时间：
1995-08-31
期刊：
影响因子：
64.8
通讯作者：
ASAI, R
中科院分区：
文献类型：
--
作者：
KONDO, S;ASAI, R
1952年，图灵提出了一个假设的分子机制，称为反应扩散系统（1），它可以从最初的均匀状态发展出周期性模式。许多基于反应扩散的理论模型被提出来解释形态发生中的模式化现象（2-4），但是，到目前为止，还没有确凿的实验证据证明在生物学领域存在这样一个系统（5-8）。海洋神仙鱼，Pomacanthus，有条纹图案，这是不固定在他们的皮肤。与哺乳动物的皮肤图案不同，在它们的身体生长过程中，它们的皮肤图案只是按比例扩大，而刺盖鱼的条纹通过图案的连续重新排列来保持线条之间的空间。虽然图案的变化取决于条纹的构造，但基于图灵系统的模拟程序可以正确地预测未来的图案。实际和模拟的图案重排之间的惊人的相似性强烈表明，反应扩散波是一个可行的机制，条纹图案的Pomacanthus。
IN 1952, Turing proposed a hypothetical molecular mechanism, called the reaction-diffusion system(1), which can develop periodic patterns from an initially homogeneous state. Many theoretical models based on reaction-diffusion have been proposed to account for patterning phenomena in morphogenesis(2-4), but, as yet, there is no conclusive experimental evidence for the existence of such a system in the field of biology(5-8). The marine angelfish, Pomacanthus, has stripe patterns which are not fixed in their skin. Unlike mammal skin patterns, which simply enlarge proportionally during their body growth, the stripes of Pomacanthus maintain the spaces between the lines by the continuous rearrangement of the patterns. Although the pattern alteration varies depending on the conformation of the stripes, a simulation program based on a Turing system can correctly predict future patterns. The striking similarity between the actual and simulated pattern rearrangement strongly suggests that a reaction-diffusion wave is a viable mechanism for the stripe pattern of Pomacanthus.