Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A
Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A
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DOI：
10.1128/jcm.00047-09
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发表时间：
2009-05-01
影响因子：
9.4
通讯作者：
Yuen, Kwok-yung
中科院分区：
文献类型：
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作者：
Lau, Susanna K. P.;Li, Kenneth S. M.;Yuen, Kwok-yung
在这项为期1年的研究中，2，912例鼻咽抽吸物中有35例（1.2%）通过逆转录-PCR检测为人副流感病毒4型（HPIV 4）阳性。HPIV 4感染者主要为幼儿和免疫功能低下的成人。与报告的HPIV 4A感染优势相反，分子亚型分型显示15例（44%）病例由HPIV 4 B引起。
In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.