AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
复制标题
DOI：
10.1242/bio.013128
复制
发表时间：
2015-09-04
期刊：
影响因子：
2.4
通讯作者：
Murray JA
中科院分区：
文献类型：
--
作者：
Randall RS;Miyashima S;Blomster T;Zhang J;Elo A;Karlberg A;Immanen J;Nieminen K;Lee JY;Kakimoto T;Blajecka K;Melnyk CW;Alcasabas A;Forzani C;Matsumoto-Kitano M;Mähönen AP;Bhalerao R;Dewitte W;Helariutta Y;Murray JA
高等植物维管系统的特征在于两个不同的发育阶段。最初，建立明确的放射状初级图案。在真双子叶植物中，这之后是次生生长，这涉及形成层的发育，并且是有效的水和营养运输以及木材形成所必需的。次生生长的调节涉及几种植物激素，细胞分裂素被认为是关键的参与者，特别是在细胞增殖的激活中，但介导这种激素控制的分子机制仍然未知。在这里，我们表明，基因编码的转录因子AINTEGUMENTA（ANT）和D型细胞周期蛋白CYCD 3;1表达在拟南芥根的维管形成层，响应细胞分裂素，都需要适当的根次生增厚。细胞分裂素对ANT和CYCD 3的调节也发生在白杨茎的二次加厚过程中，这表明这代表了一种保守的调节机制。
Higher plant vasculature is characterized by two distinct developmental phases. Initially, a well-defined radial primary pattern is established. In eudicots, this is followed by secondary growth, which involves development of the cambium and is required for efficient water and nutrient transport and wood formation. Regulation of secondary growth involves several phytohormones, and cytokinins have been implicated as key players, particularly in the activation of cell proliferation, but the molecular mechanisms mediating this hormonal control remain unknown. Here we show that the genes encoding the transcription factor AINTEGUMENTA (ANT) and the D-type cyclin CYCD3;1 are expressed in the vascular cambium of Arabidopsis roots, respond to cytokinins and are both required for proper root secondary thickening. Cytokinin regulation of ANT and CYCD3 also occurs during secondary thickening of poplar stems, suggesting this represents a conserved regulatory mechanism.