The impact of COVID-19 on rheumatology patients in a large UK centre using an innovative data collection technique: prevalence and effect of social shielding.
The impact of COVID-19 on rheumatology patients in a large UK centre using an innovative data collection technique: prevalence and effect of social shielding.
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DOI：
10.1007/s00296-021-04797-4
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发表时间：
2021-04
影响因子：
4
通讯作者：
Bateman J
中科院分区：
文献类型：
--
作者：
Cleaton N;Raizada S;Barkham N;Venkatachalam S;Sheeran TP;Adizie T;Sapkota H;Singh BM;Bateman J
我们试图深入了解COVID-19的流行情况以及严格的社交距离（屏蔽）对来自英国一家大型中心的大型风湿病（RD）随访患者队列的影响。我们将COVID-19相关死亡、筛查和感染率与我们的研发人群（1.2.20-1.5.20）联系起来，并通过通过链接的移动的手机短信传达的调查数据稽查了活跃的风湿病随访患者。我们评估流行病学，严格的社会距离（屏蔽）和生活质量（HRQoL）的影响，简表12（SF 12）。有10，387例主动随访患者，7911例有关联的移动的号码。12/10，387例RD患者死于COVID-19（0.12%）;当地人口4131/7，415，149（0.12%）。对于使用移动的电话的患者，1693/7911（21%）例患者有应答，其中1605例患者完成了SF 12。炎性关节炎占1174/1693例（69%）; 792/1693例（47%）为遮蔽性关节炎。其次是提供防护/保持距离的建议，占1372/1693（81%）。61/1693（4%）报告了COVID-19（24/61屏蔽）; COVID和非COVID患者的药物分布相似。心理SF 12（MCS）而非身体（PCS）成分评分在COVID（60）与非COVID（1545）中较低，平均差异：MCS，− 3.3; 95%CI − 5.2至− 1.4，P < 0.001; PCS，− 0.4; 95%CI，− 2.1至1.3）。在1545名COVID阴性患者中，那些屏蔽的MCS（-2.1; 95%CI-2.8至-1.4）和PCS（-3.1，95%CI-3.7至-2.5）较低，均P < 0.001。与当地一般人群相比，我们的整个研发队列的新冠肺炎死亡人数并没有过多。我们的调查数据表明，屏蔽对RD的心理和身体健康都有不利影响。这些数据拓宽了我们对屏蔽的理解，表明需要进一步研究。
We sought to gain insight into the prevalence of COVID-19 and the impact stringent social distancing (shielding) has had on a large cohort of rheumatology (RD) follow-up patients from a single large UK centre. We linked COVID-19-related deaths, screening and infection rates to our RD population (1.2.20–1.5.20) and audited active rheumatology follow-up patients through survey data communicated via a linked mobile phone SMS message. We assessed epidemiology, effect of stringent social distancing (shielding) and quality of life (HRQoL) by Short Form 12 (SF12). There were 10,387 active follow-up patients, 7911 had linked mobile numbers. 12/10,387 RD patients died from COVID-19 (0.12%); local population 4131/7,415,149 (0.12%). For patients with mobile phones, 1693/7911 (21%) responded and of these, 1605 completed the SF12. Inflammatory arthritis predominated 1174/1693 (69%); 792/1693 (47%) were shielding. Advice on shielding/distancing was followed by 1372/1693(81%). 61/1693 (4%) reported COVID-19 (24/61 shielding); medication distribution was similar in COVID and non-COVID patients. Mental SF12 (MCS) but not physical (PCS) component scores were lower in COVID (60) vs. non-COVID (1545), mean differences: MCS, − 3.3; 95% CI − 5.2 to − 1.4, P < 0.001; PCS, − 0.4; 95% CI, − 2.1 to 1.3). In 1545 COVID-negative patients, those shielding had lower MCS (− 2.1; 95% CI − 2.8 to − 1.4) and PCS (− 3.1, 95% CI − 3.7 to − 2.5), both P < 0.001. Our full RD cohort had no excess of COVID deaths compared to the general local population. Our survey data suggest that shielding adversely affects both mental and physical health in RD. These data broaden our understanding of shielding, indicating need for further study.
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作者：
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