Top-down reorganization of activity in the visual pathway after learning a shape identification task
Top-down reorganization of activity in the visual pathway after learning a shape identification task
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DOI：
10.1016/j.neuron.2005.05.014
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发表时间：
2005-06-02
期刊：
影响因子：
16.2
通讯作者：
Gilbert, CD
中科院分区：
文献类型：
--
作者：
Sigman, M;Pan, H;Gilbert, CD
形状识别的学习导致了整个视觉通路激活的全局变化，正如全脑fMRI所揭示的那样。在形状识别任务中进行广泛的训练后，与未经训练的形状相关的大脑活动显示：（1）视网膜皮层（RC）的活动水平增加，（2）外侧枕叶皮层（LO）的激活减少，（3）背侧注意网络减少。此外，RC激活与性能的相关性更高（LO激活与性能的相关性更低）。当在训练条件下比较目标存在和目标不存在的试验时，我们观察到背侧注意力网络出现了类似的下降，但视觉皮层没有。这些研究结果表明，作为学习的结果，在视觉通路中的活动的大规模重组，与RC变得更多的参与（和LO，较少参与），这些变化是触发自上而下的方式取决于执行的感知任务。
Learning in shape identification led to global changes in activation across the entire visual pathway, as revealed with whole-brain fMRI. Following extensive training in a shape identification task, brain activity associated with trained shapes relative to the untrained shapes showed: (1) an increased level of activity in retinotopic cortex (RC), (2) a decrease in activation of the lateral occipital cortex (LO), and (3) a decrease in the dorsal attentional network. In addition, RC activations became more correlated (and LO activation, less correlated) with performance. When comparing target-present and target-absent trials within the trained condition, we observed a similar decrease in the dorsal attentional network but not in the visual cortices. These findings indicate a large-scale reorganization of activity in the visual pathway as a result of learning, with the RC becoming more involved (and the LO, less involved) and that these changes are triggered in a top-down manner depending on the perceptual task performed.