Validating the PROMIS cognitive function short form in cancer survivors.
Validating the PROMIS cognitive function short form in cancer survivors.
复制标题
验证癌症幸存者的 PROMIS 认知功能简表。
DOI：
10.1007/s10549-023-06968-2
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发表时间：
2023
影响因子：
3.8
通讯作者：
Ganz,PatriciaA
中科院分区：
文献类型：
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作者：
Henneghan,AshleyM;VanDyk,Kathleen;Zhou,Xingtao;Moore,RaeanneC;Root,JamesC;Ahles,TimA;Nakamura,ZevM;Mandeblatt,Jeanne;Ganz,PatriciaA
目的患者报告的结果测量信息系统认知功能简写8a表(Promis Cog)可以为研究和临床治疗中经常使用的癌症治疗认知功能评估(FACT-Cog)提供一个更短、更有用的替代方案。本研究旨在检验PROMIS COG在3个乳腺癌存活者样本中的收敛效度和内部信度，并探讨临床切入点。通过评估派生的Promis Cog与抑郁、焦虑、压力、疲劳、睡眠、孤独、事实Cog之间的相关强度来确定收敛效度。结果纳入3例乳腺癌存活者(N = 4 71例，N = 132例，N = 90例)。相关系数的绝对值在0.21到0.82之间，P‘s <； 为0.001，与18项认知障碍认知障碍量表的相关系数相当。ROC曲线图显示联合样本的临床界& 为34。结论8项PROMIS COG在乳腺癌存活者中表现出良好的收敛效度和内部信度，与18项FACT-COG PCI值相当。Promis Cog 8a是一种简短的自我报告测量方法，可以很容易地纳入与癌症相关的认知障碍研究设计或用于临床环境。
PurposeThe Patient-Reported Outcome Measurement Information System Cognitive Function Short Form 8a (PROMIS Cog) could provide a shorter, useful alternative to the often used Functional Assessment of Cancer Therapy – Cognition (FACT-Cog) in research and clinical care. This study aimed to determine the convergent validity and internal reliability of the PROMIS Cog in 3 separate samples of breast cancer survivors and to explore clinical cut points.MethodsData from three samples of breast cancer survivors were used for this secondary analysis. Convergent validity was determined by evaluating correlation strength among the derived PROMIS Cog and measures of depression, anxiety, stress, fatigue, sleep, loneliness, the FACT-Cog . Clinical cut-points for the PROMIS Cog were determined by plotting the receiver operating characteristic curves.Results3 samples of breast cancer survivors (N = 471, N = 132, N = 90) were included. Absolute values of correlations demonstrating convergent validity ranged from 0.21 to 0.82, p’s < 0.001, and were comparable to correlations with the full FACT-Cog 18 item perceived cognitive impairments (PCI) scale. ROC curve plots indicated a clinical cut off < 34 for the combined sample.ConclusionThe 8-item PROMIS Cog demonstrated good convergent validity and internal reliability in breast cancer survivors, comparable to the 18-item FACT-Cog PCI. The PROMIS Cog 8a is a brief self-report measure that can be easily incorporated into cancer-related cognitive impairment research designs or used in clinical settings.