Antagonism of carbon monoxide-mediated brain lipid peroxidation by hyperbaric oxygen.
Antagonism of carbon monoxide-mediated brain lipid peroxidation by hyperbaric oxygen.
复制标题
高压氧对抗一氧化碳介导的脑脂质过氧化。
DOI：
10.1016/0041-008x(90)90195-z
复制
发表时间：
1990
影响因子：
3.8
通讯作者：
Thom,SR
中科院分区：
文献类型：
--
作者：
Thom,SR
The effects of oxygen at 1, 2, and 3, atmospheres absolute (ATA) were assessed on brain lipid peroxidation caused by carbon monoxide (CO) poisoning in a rat model. Oxygen at 3 ATA, but not 1 ATA, was found to prevent brain lipid peroxidation when administered to rats for 45 min, beginning 45 min subsequent to CO poisoning. Oxygen at 2 ATA had an intermediate effect. The action of hyperbaric oxygen could not be attributed to a more rapid diminution of carboxyhemoglobin, and appears to occur at the level of the brain tissue.
