Motion sickness susceptibility associated with visually induced postural instability and cardiac autonomic responses in healthy subjects
Motion sickness susceptibility associated with visually induced postural instability and cardiac autonomic responses in healthy subjects
复制标题
健康受试者晕动病的易感性与视觉诱发的姿势不稳定和心脏自主反应相关
作者：
Yoichi Yokota;M. Aoki;K. Mizuta;Yatsuji Ito;N. Isu
结论运动病易感性可能与姿势摇摆和自主神经反应有关。在暴露于刺激的心脏交感迷走神经平衡的特点可能是一个标记的个体易感性晕动病。目的探讨模拟视觉运动环境下姿势和自主神经反应与运动病易感性的关系。材料和方法15名健康受试者暴露于正弦振荡的视觉运动在滚动的频率为0.1-0.4 Hz。记录姿势摇摆和呼吸频率，并获得心电图，从中计算心率变异性（HRV），以探测心脏交感神经和副交感神经活动。结果在使用标准化问卷评定的对运动病易感性低的受试者中，在任何运动频率下，视觉刺激对姿势摇摆或HRV没有显著影响。运动病易感性高的受试者表现出明显的视觉刺激引起的姿势不稳定（p<0.01）。0.1Hz视觉刺激使HRV的低频功率（LF）增加，高频功率（HF）降低，LF：HF比值增加（p<0.05）。
Conclusions This study supports the hypothesis that postural sway and autonomic responses to moving visual stimuli may be associated with motion sickness susceptibility. Characteristics of the cardiac sympathovagal balance during exposure to provocative stimulation may be a marker of individual susceptibility to motion sickness. Objective To assess the relationship between postural and autonomic responses to a simulated visual motion environment and reported susceptibility to motion sickness. Material and methods Fifteen healthy subjects were exposed to sinusoidally oscillating visual motion in roll at frequencies of 0.1–0.4 Hz. Recordings were made of postural sway and respiratory frequency and electrocardiograms were obtained from which heart rate variability (HRV) was computed in order to probe cardiac sympathetic and parasympathetic activity. Results In subjects with a low susceptibility to motion sickness as rated using a standardized questionnaire, there was no significant effect of visual stimulus on postural sway or HRV at any frequency of motion. Subjects with a high susceptibility to motion sickness showed significant postural instability induced by visual stimuli (p<0.01). Visual stimuli presented at a frequency of 0.1 Hz significantly increased the low-frequency power (LF) of HRV, decreased the high-frequency power (HF) of HRV and increased the LF:HF ratio in these subjects (p<0.05).