Evolving Epidemiology of Hepatitis C Virus in the United States
Evolving Epidemiology of Hepatitis C Virus in the United States
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DOI：
10.1093/cid/cis393
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发表时间：
2012-07-15
影响因子：
11.8
通讯作者：
Holmberg, Scott D.
中科院分区：
文献类型：
--
作者：
Klevens, R. Monina;Hu, Dale J.;Holmberg, Scott D.
在美国，丙型肝炎病毒（HCV）感染对健康和医疗保健的影响是传染病医生面临的一个主要问题。虽然HCV感染的发病率在过去20年里显著下降，但在美国，300万或更多的居民慢性感染导致的疾病和死亡人数超过了人类免疫缺陷病毒(HIV)/艾滋病。目前丙型肝炎病毒感染的流行病学趋势包括，开始使用口服处方阿片类药物的年轻人（通常是郊区的海洛因注射吸毒者）明显增加；非医院保健（诊所）环境中的感染；以及艾滋病毒感染者之间的性传播。传染病医生将越来越多地承担诊断和治疗HCV患者的责任。了解这些患者是如何被感染的，对于确定筛查和治疗对象非常重要。
The impact of hepatitis C virus (HCV) infection on health and medical care in the United States is a major problem for infectious disease physicians. Although the incidence of HCV infection has declined markedly in the past 2 decades, chronic infection in 3 million or more residents now accounts for more disease and death in the United States than does human immunodeficiency virus (HIV)/AIDS. Current trends in the epidemiology of HCV infection include an apparent increase in young, often suburban heroin injection drug users who initiate use with oral prescription opioid drugs; infections in nonhospital healthcare (clinic) settings; and sexual transmission among HIV-infected persons. Infectious disease physicians will increasingly have the responsibility of diagnosing and treating HCV patients. An understanding of how these patients were infected is important for determining whom to screen and treat.