Neuropsychological function in manganese alloy plant workers
Neuropsychological function in manganese alloy plant workers
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DOI：
10.1007/s00420-003-0491-0
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发表时间：
2004-05-01
影响因子：
3
通讯作者：
Thomassen, Y
中科院分区：
文献类型：
--
作者：
Bast-Pettersen, R;Ellingsen, DG;Thomassen, Y
目标。目的是调查锰 (Mn) 暴露对锰合金生产工厂工人神经系统的潜在影响。方法。将 100 名锰合金厂男性工人与 100 名年龄匹配的参考对象进行了比较。受试者接受了全面的神经心理学测试。通过测量工作室空气、血液和尿液中的锰浓度来评估暴露情况。结果。工作室空气中可吸入锰的几何平均（GM）浓度为301 mug/m(3)。全血中 Mn 的 GM 浓度（181 nmol/l vs 160 nmol/l）（P=0.002）和尿液（0.9 nmol/mmol 肌酐 vs 0.4 nmol/mmol 肌酐）（P
Objectives. The objective was to investigate potential nervous system effects of manganese (Mn) exposure in workers employed in manganese-alloy-producing plants. Methods. One hundred male Mn alloy plant workers were compared with 100 age-matched referents. The subjects were examined with a comprehensive neuropsychological test battery. Exposure was assessed by measurement of Mn concentrations in the workroom air, blood and urine. Results. The geometric mean (GM) concentration of inhalable Mn in workroom air was 301 mug/m(3). The GM concentration of Mn in whole blood (181 nmol/l vs 160 nmol/l) (P=0.002) and urine (0.9 nmol/mmol creatinine vs 0.4 nmol/mmol creatinine) (P