THE SEROTYPES OF STREPTOCOCCUS-PYOGENES PRESENT IN BRITAIN DURING 1980-1990 AND THEIR ASSOCIATION WITH DISEASE
THE SEROTYPES OF STREPTOCOCCUS-PYOGENES PRESENT IN BRITAIN DURING 1980-1990 AND THEIR ASSOCIATION WITH DISEASE
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DOI：
10.1099/00222615-39-3-165
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发表时间：
1993-09-01
影响因子：
3
通讯作者：
GAWORZEWSKA, ET
中科院分区：
文献类型：
--
作者：
COLMAN, G;TANNA, A;GAWORZEWSKA, ET
对1980-1990年在英国分离的16909株化脓性链球菌(兰斯菲尔德A组)进行了T蛋白和M蛋白抗原检测。92.6%的菌株检出一种或另一种M抗原。部分血清型如M3和M12的分离物数量年际间变化不大，但由M1和M49血清型菌株引起的全国性流行持续数年。血清型M1和M3的分离株尤其与侵袭性疾病和致命性感染有关。M80、M81血清型和PT180、PT1658、PT5757临时型的代表菌株最多见于脓皮病患者。在30个血清型中检测到红霉素耐药，但有一半的耐药株属于M4型。
A total of 16 909 cultures of Streptococcus pyogenes (Lancefield group A) isolated in Britain during 1980-90 were examined for T- and M-protein antigens. One or other M antigen was detected in 92.6% of the strains. The numbers of isolates of some serotypes, such as M3 and M12, did not show great variation from year-to-year, whereas there were nationwide epidemics, extending over several years, caused by strains of serotypes M1 and M49. Isolates of serotypes M1 and M3 were associated particularly with invasive disease and fatal infections. Representatives of serotypes M80, M81 and the provisional types PT180, PT1658 and PT5757 were isolated most often from cases of pyoderma. Erythromycin resistance was detected in 30 serotypes but one half of all of the resistant isolates belonged to serotype M4.