Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations.
Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations.
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DOI：
10.1177/2515135519826481
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发表时间：
2019-01-01
影响因子：
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通讯作者：
Regan, Annette K
中科院分区：
文献类型：
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作者：
Sullivan, Sheena G;Price, Olivia H;Regan, Annette K
疫苗接种是预防流感最实用的手段。流感疫苗需要经常更新，以跟上病毒抗原漂移的步伐，因此疫苗的有效性（有时甚至是安全性）可能会因季节而异。世界卫生组织建议优先接种流感疫苗的三个重点人群是孕妇、5岁以下儿童和老年人。本综述讨论了流感的负担以及推荐给这些人群的流感疫苗的安全性和有效性。
Vaccination is the most practical means available for preventing influenza. Influenza vaccines require frequent updates to keep pace with antigenic drift of the virus, and the effectiveness, and sometimes the safety, of the vaccine can therefore vary from season to season. Three key populations that the World Health Organization recommends should be prioritized for influenza vaccination are pregnant women, children younger than 5years of age and the elderly. This review discusses the burden of influenza and the safety and effectiveness profile of influenza vaccines recommended for these groups.