BACTERICIDAL PROPERTIES OF PERACETIC-ACID AND HYDROGEN-PEROXIDE, ALONE AND IN COMBINATION, AND CHLORINE AND FORMALDEHYDE AGAINST BACTERIAL WATER STRAINS
BACTERICIDAL PROPERTIES OF PERACETIC-ACID AND HYDROGEN-PEROXIDE, ALONE AND IN COMBINATION, AND CHLORINE AND FORMALDEHYDE AGAINST BACTERIAL WATER STRAINS
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DOI：
10.1139/m92-104
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发表时间：
1992-07-01
影响因子：
2.8
通讯作者：
APTEL, P
中科院分区：
文献类型：
--
作者：
ALASRI, A;ROQUES, C;APTEL, P
采用快速微量法对过氧乙酸、过氧化氢、氯和甲醛的体外杀菌性能进行了比较。还测试了过氧乙酸和过氧化氢的组合，以评估相互作用。对这些广泛用作消毒剂的药剂对水分离菌和培养收集菌的活性进行了评价。过氧乙酸和氯具有良好的抑菌活性，可较快杀灭10(5)个细菌/mL。过氧化氢和甲醛的杀菌活性随时间的变化最低。过氧乙酸和过氧化氢的组合，通过棋盘格微法测试，发现是协同的。对于给定的过氧乙酸和过氧化氢混合物，用时间确定了最小杀菌浓度。灭菌浓度的测定表明，随着接触时间的增加，协同作用保持不变。在体外提供有趣活性的化学物质处理的最短时间内，对超滤膜的消毒进行了浓度测试。证实了过氧化合物的杀菌活性，并在工作条件下保持了协同作用。氯在膜上使用时失去了效果。
The bactericidal properties of peracetic acid, hydrogen peroxide, chlorine, and formaldehyde were compared in vitro using a rapid micromethod. A combination of peracetic acid and hydrogen peroxide was also tested to assess interactions. The activities of these agents, which are widely used as disinfectants, were evaluated against water isolates and culture collection strains. Peracetic acid and chlorine exhibited an excellent antimicrobial activity, with a relatively rapid destruction of 10(5) bacteria/mL. The time-dependent bactericidal activities of hydrogen peroxide and formaldehyde were the lowest. The combination of peracetic acid and hydrogen peroxide, tested by a checkerboard micromethod, was found to be synergistic. The minimal bactericidal concentration was established in terms of time for a given mixture of peracetic acid and hydrogen peroxide. Determination of bactericidal concentrations showed that synergy was maintained with increasing contact time. Concentrations for minimal times of treatment by chemicals that provided interesting activities in vitro were tested for disinfection of ultrafiltration membranes. The bactericidal activities of peroxygen compounds were confirmed and synergism was maintained in working conditions. Chlorine showed a loss of efficacy when used on membranes.