LC-TOF-MSによる農産物中の残留農薬一斉分析の検討
LC-TOF-MSによる農産物中の残留農薬一斉分析の検討
复制标题
LC-TOF-MS同时分析农产品中农药残留的研究
DOI：
10.3358/shokueishi.53.255
复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
松田 りえ子
中科院分区：
文献类型：
--
作者：
静夏 齊藤;了 根本;松田 りえ子
研究了高效液相色谱飞行时间质谱仪(LC-TOF-MS)测定农产品中农药残留的可行性。对TOF-MS监测目标离子及其碎片离子的条件进行了仔细的优化。采用基质匹配标准对所建立的LC-TOF-MS方法进行了评价，测定了大豆和菠菜中的154种农药。大多数受试农药在浓度为0.01 mg/kg时均未观察到显著的基质效应，其中145种农药的定量限小于0.01 mg/kg(S/N>；10)。此外，空白提取物的色谱图未观察到明显干扰。这些结果表明，LC-TOF-MS检测技术有望成为农产品中农药多残留分析的有力工具。
: The applicability of liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS) for determining pesticide residues in agricultural products was investigated. TOF-MS conditions for monitoring target ions, together with their fragment ions, were carefully optimized. The developed LC-TOF-MS method was evaluated for 154 pesticides in soybean and spinach by using matrix-matched standards. No significant matrix effect was observed for most of the tested pesticides at a concentration level of 0.01 mg/kg, where the limits of quantification were less than 0.01 mg/kg for 145 of the 154 pesticides (S/N>10). In addition, no significant interference was observed in the chromatograms of the blank extracts. These results indicate that LC-TOF-MS determination may become a powerful tool for multi-residue analysis of pesticides in agricultural products.