Endolymphatic hydrops revealed by magnetic resonance imaging in patients with atypical Meniere's disease
Endolymphatic hydrops revealed by magnetic resonance imaging in patients with atypical Meniere's disease
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DOI：
10.3109/00016489.2012.726374
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发表时间：
2013-02-01
影响因子：
1.4
通讯作者：
Nakashima, Tsutomu
中科院分区：
文献类型：
--
作者：
Kato, Masahiro;Sugiura, Makoto;Nakashima, Tsutomu
结论：我们的研究表明，非典型梅尼埃病患者在耳蜗和前庭均存在内淋巴水肿（EH）。使用影像学方法，我们提供证据，非典型梅尼埃病是一个真正的变异经典梅尼埃病。目的：本研究的目的是探讨非典型梅尼埃病（耳蜗和前庭梅尼埃病）患者的内淋巴间隙图像。方法：64例患者分为两组。第一组包括36名无眩晕的波动性听力损失患者，作为耳蜗梅尼埃病（CMD）的候选者。第二组包括28例复发性眩晕但无听力损失的患者，作为前庭梅尼埃病（VMD）的候选者。患者经非腔内或静脉注射钆增强剂后行3t磁共振成像（MRI）。我们用MRI评估EH。结果：36例56耳CMD患者中，耳蜗EH 38例，前庭EH 44例。在56耳（28例）VMD中，29耳蜗EH， 47前庭EH。VMD组在EH分布上有明显的前庭优势，而CMD组在EH分布上没有明显的区域优势。
Conclusion: Our study showed that patients with atypical Meniere's disease had endolymphatic hydrops (EH) in both the cochlea and the vestibule. Using an imaging method, we provide evidence that atypical Meniere's disease is a true variant of classic Meniere's disease. Objectives: The aim of present study was to investigate images of the endolymphatic space in patients with atypical Meniere's disease (cochlear and vestibular Meniere's disease). Methods: Sixty-four patients divided into two groups were enrolled in this study. The first group included 36 patients who had fluctuating hearing loss without vertigo, as candidates for cochlear Meniere's disease (CMD). The second group included 28 patients who had recurrent vertigo without hearing loss, as candidates for vestibular Meniere's disease (VMD). The patients underwent 3 T magnetic resonance imaging (MRI) after injection of gadolinium enhancement medium intratympanically or intravenously. We evaluated EH using MRI. Results: Of 56 ears (36 patients) with CMD, 38 showed EH in the cochlea and 44 showed EH in the vestibule. Of 56 ears (28 patients) with VMD, 29 showed EH in the cochlea and 47 showed EH in the vestibule. The VMD group had a significant vestibular predominance in EH distribution whereas the CMD group showed no significant regional predominance of EH.