A model of cell-wall dynamics during sporulation in Bacillus subtilis.
A model of cell-wall dynamics during sporulation in Bacillus subtilis.
复制标题
枯草芽孢杆菌孢子形成过程中的细胞壁动力学模型。
作者:
Yap LW
To survive starvation, Bacillus subtilis forms durable spores. After asymmetric cell division, the septum grows around the forespore in a process called engulfment, but the mechanism of force generation is unknown. Here, we derived a novel biophysical model for the dynamics of cell-wall remodeling during engulfment based on a balancing of dissipative, active, and mechanical forces. By plotting phase diagrams, we predict that sporulation is promoted by a line tension from the attachment of the septum to the outer cell wall, as well as by an imbalance in turgor pressures in the mother-cell and forespore compartments. We also predict that significant mother-cell growth hinders engulfment. Hence, relatively simple physical principles may guide this complex biological process.
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影响因子:
6.1
作者:
G. Koch;D. Richter
通讯作者:
D. Richter
DOI:
--
发表时间:
1979
期刊:
影响因子:
--
作者:
E. Freese;Juan M. Lopez;E. Freese
通讯作者:
E. Freese
影响因子:
7.7
作者:
Nikola Ojkic;Javier López;K. Pogliano;R. G. Endres
通讯作者:
R. G. Endres
影响因子:
3.6
作者:
Pedrido, Maria E.;de Ona, Paula;Grau, Roberto
通讯作者:
Grau, Roberto
影响因子:
10.5
作者:
Doan, Thierry;Coleman, Jeff;Rudner, David Z.
通讯作者:
Rudner, David Z.