Periodic lateralized epileptiform discharges (PLEDs) as early indicator of stroke in full-term newborns
Periodic lateralized epileptiform discharges (PLEDs) as early indicator of stroke in full-term newborns
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DOI：
10.1055/s-2000-7454
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发表时间：
2000-08-01
期刊：
影响因子：
1.4
通讯作者：
Guzzetta, F
中科院分区：
文献类型：
--
作者：
Randò, T;Ricci, D;Guzzetta, F
我们报告两个新生儿惊厥的脑电图周期性偏侧癫痫样放电。在这两个新生儿中，EEG异常在癫痫发作后不久就出现了，当时颅超声扫描被认为是正常的。随后的磁共振成像扫描显示两名患者均发生脑梗死。在1例病例中，MRI上病变的定位与EEG异常一致，这通常见于局灶性病变的成人。另一名婴儿表现出类似的EEG异常，但她的MRI显示基底神经节局部病变，据报道，这也参与了这些异常的发生。
We report on periodic lateralized epileptiform discharges (PLEDs) on EEG in two infants with neonatal convulsions. In both neonates, the EEG abnormalities were seen soon after the onset of seizures, at a time when cranial ultrasound scans were thought to be normal. Subsequent Magnetic Resonance Imaging scans demonstrated cerebral infarction in both patients. In one case, the localisation of the lesion on MRI was concordant with that of the EEG abnormalities, as usually observed in adults with focal lesions. The other infant showed similar EEG abnormalities, but her MRI showed a localised lesion in the basal ganglia, which has also been reported to be involved in the genesis bf these abnormalities.