Attitudes and psychological impact of genetic testing, genetic counseling, and breast cancer risk assessment among women at increased risk.
Attitudes and psychological impact of genetic testing, genetic counseling, and breast cancer risk assessment among women at increased risk.
复制标题
DOI：
10.1188/03.onf.241-246
复制
发表时间：
2003-03-01
影响因子：
1.9
通讯作者：
Hutson, Sadie Pauline
中科院分区：
文献类型：
--
作者：
Hutson, Sadie Pauline
目的/目的：回顾有乳腺癌家族史的妇女的心理功能、遗传咨询对高危妇女的影响以及她们参与和描述乳腺癌风险评估项目的相关研究。资料来源：万维网上发表的文章和资料。资料综合：这些来源的结果表明，有乳腺癌家族史的女性存在潜在的心理困扰。这可能会增加或减少他们的监督做法。随着商业基因检测BRCA 1和BRCA 2的开始，研究人员已经研究了一些最初的心理社会影响的遗传信息对妇女在highrisk.CONCLUSIONS：妇女乳腺癌家族史有很高的兴趣在基因检测BRCA 1和BRCA 2突变。他们有一个潜在的心理困扰水平，是不能通过遗传咨询缓解。他们倾向于陈述想要和不想要测试的原因，而不是两极对立。参加乳腺癌风险评估项目的女性往往是自我推荐的，白人，受过良好教育的，中等或较高收入的。对有色人种妇女和那些受教育程度较低、社会经济地位较低的妇女的研究存在很大差距。对乳腺癌的影响：护士和其他医疗保健专业人员应该利用与她们的情感和医疗需求有关的现有信息，为遗传性乳腺癌风险增加的妇女量身定制护理。关于基因检测、遗传咨询和乳腺癌风险评估的决定是高度个性化的。因此，医疗保健专业人员应该谨慎对待任何关于女性乳腺癌风险的概括。
PURPOSE/OBJECTIVES: To review research related to the psychological functioning of women with family histories of breast cancer, the impact of genetic counseling on women at increased risk, and their participation in and description of breast cancer risk evaluation programs.DATA SOURCES: Published articles and material from the World Wide Web.DATA SYNTHESIS: Findings from these sources suggest an underlying level of psychological distress in women with family histories of breast cancer. This may either increase or decrease their surveillance practices. With the onset of commercial genetic testing for BRCA1 and BRCA2, researchers have studied some of the initial psychosocial effects of genetic information on women at high risk.CONCLUSIONS: Women with family histories of breast cancer have a very high interest in genetic testing for BRCA1 and BRCA2 mutations. They have an underlying level of psychological distress that is not relieved by genetic counseling. They tend to state reasons for wanting and not wanting testing that are not polar opposites. Women who attend breast cancer risk assessment programs tend to be self-referred, Caucasian, well-educated, and of middle or upper income status. Large gaps exist in the research on women of color and those who are less educated and of lower socioeconomic status.IMPLICATIONS FOR NURSING: Nurses and other healthcare professionals should tailor care given to women at increased risk for hereditary breast cancer by using the current information related to their emotional and medical needs. Decisions regarding genetic testing, genetic counseling, and breast cancer risk assessment are highly individualized. Thus, healthcare professionals should be cautious regarding any generalizations about women at risk for breast cancer.