COMPARATIVE-STUDY OF THE INTRINSIC MECHANICAL-PROPERTIES OF THE HUMAN ACETABULAR AND FEMORAL-HEAD CARTILAGE
COMPARATIVE-STUDY OF THE INTRINSIC MECHANICAL-PROPERTIES OF THE HUMAN ACETABULAR AND FEMORAL-HEAD CARTILAGE
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DOI：
10.1002/jor.1100120306
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发表时间：
1994-05-01
影响因子：
2.8
通讯作者：
DZIDA, FJ
中科院分区：
文献类型：
--
作者：
ATHANASIOU, KA;AGARWAL, A;DZIDA, FJ
采用双相蠕变压痕法和自动压痕仪测量了10个人髋关节正常关节软骨的总模量、泊松比、渗透率、厚度、蠕变和恢复平衡时间以及恢复百分比。这些属性被映射到区域，以检查髋臼和股骨头特定部位退行性病变发展中涉及的力学因素。结果表明，髋臼和股骨头的这些特性在区域上以及两个解剖结构之间存在显着差异。具体而言，发现股骨头上内侧的软骨具有比髋臼中其解剖学上对应的关节面大41%的总模量。此外，股骨头的上内侧在髋关节内具有最大的聚合模量（1.816 MPa）。在坐位期间，股骨头的下部与前髋臼接触，并且前髋臼具有比下部股骨头大53%的聚合模量。股骨头上的中央凹下方的该区域在髋关节内具有最小的聚集模量（0.814MPa）。相对关节面的压缩模量的这些不匹配可能导致髋臼内侧上部和股骨头下部的软骨退化。我们的研究结果支持了临床观察，这些地区是早期变性的频繁网站。
Biphasic creep indentation methodology and an automated indentation apparatus were used to measure the aggregate modulus, Poisson's ratio, permeability, thickness, creep and recovery equilibrium times, and percentage of recovery of normal articular cartilage in 10 human hip joints. These properties were mapped regionally to examine the mechanical factors involved in the development of site-specific degenerative lesions in the acetabulum and femoral head. The results indicate that there are significant differences between these properties regionally in the acetabulum and femoral head and between the two anatomical structures. Specifically, it was found that cartilage in the superomedial aspect of the femoral head has a 41% larger aggregate modulus than its anatomically corresponding articulating surface in the acetabulum. In addition, the superomedial aspect of the femoral head has the greatest aggregate modulus (1.816 MPa) within the hip joint. During sitting, the inferior portion of the femoral head is in contact with the anterior acetabulum, and the anterior acetabulum has a 53% greater aggregate modulus than the inferior femoral head. This area below the fovea on the femoral head has the least aggregate modulus (0.814 MPa) within the hip joint. These mismatches in the compressive modulus of opposing articulating surfaces may contribute to degeneration of cartilage in the superomedial acetabulum and the inferior femoral head. Our findings support the clinical observation that these areas are frequent sites of early degeneration.