Imparting nanoparticle function with size-controlled amphiphilic polymers
Imparting nanoparticle function with size-controlled amphiphilic polymers
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DOI：
10.1021/ja711252n
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发表时间：
2008-03-26
影响因子：
15
通讯作者：
Snee, Preston T.
中科院分区：
文献类型：
--
作者：
Chen, Yingchuan;Thakar, Rahul;Snee, Preston T.
在这里，我们报告了我们的方法的水增溶和随后的功能化的各种纳米粒子系统的两亲性聚合物含有内置的“化学手柄”。我们已经使用这些聚合物，其具有窄的多分散性指数，赋予水溶性和对目标物质的化学敏感性（这里：pH值）。这些材料体系在水性条件下具有高的化学缀合效率，其可用于产生各种化学和生物多功能材料。
Herein we report our method of water solubilization and subsequent functionalization of a variety of nanoparticle systems with amphiphilic polymers containing build-in "chemical handles". We have used these polymers, which have narrow polydispersity indices, to impart water solubility and chemical sensitivity toward targeted species (here: pH). These material systems have high chemical conjugation efficiencies in aqueous conditions which may be used to create a variety of chemical and biological multifunctional materials.