Analysis of Vertebral Bone Strength, Fracture Pattern, and Fracture Location: A Validation Study Using a Computed Tomography-Based Nonlinear Finite Element Analysis
Analysis of Vertebral Bone Strength, Fracture Pattern, and Fracture Location: A Validation Study Using a Computed Tomography-Based Nonlinear Finite Element Analysis
复制标题
DOI：
10.14336/ad.2014.0621
复制
发表时间：
2015-06-01
影响因子：
7.4
通讯作者：
Imai, Kazuhiro
中科院分区：
文献类型：
--
作者：
Imai, Kazuhiro
有限元分析（FEA）是工程力学中发展起来的一种先进的结构应力分析计算机技术。由于椎骨的压缩行为表现出非线性行为，因此应利用非线性有限元分析来分析临床椎体骨折。本文介绍了一种基于计算机断层扫描的非线性有限元分析 (CT/FEA)，用于分析椎骨强度、骨折模式和骨折位置。通过对人体尸体标本进行实验机械测试来验证 CT/FEA 的准确性。使用 CT/FEA 准确分析椎骨强度和椎体表面的最小主应变。还准确模拟了实验断裂模式和断裂位置。通过评估 CT/FEA 的精度来优化单元尺寸，假设最佳单元尺寸为 2 mm。预计 CT/FEA 在分析椎体骨折风险和评估骨质疏松症治疗效果方面将具有重要价值。
Finite element analysis (FEA) is an advanced computer technique of structural stress analysis developed in engineering mechanics. Because the compressive behavior of vertebral bone shows nonlinear behavior, a nonlinear FEA should be utilized to analyze the clinical vertebral fracture. In this article, a computed tomography-based nonlinear FEA (CT/FEA) to analyze the vertebral bone strength, fracture pattern, and fracture location is introduced. The accuracy of the CT/FEA was validated by performing experimental mechanical testing with human cadaveric specimens. Vertebral bone strength and the minimum principal strain at the vertebral surface were accurately analyzed using the CT/FEA. The experimental fracture pattern and fracture location were also accurately simulated. Optimization of the element size was performed by assessing the accuracy of the CT/FEA, and the optimum element size was assumed to be 2 mm. It is expected that the CT/FEA will be valuable in analyzing vertebral fracture risk and assessing therapeutic effects on osteoporosis.