Biomechanical integrity score of the female pelvic floor.
Biomechanical integrity score of the female pelvic floor.
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DOI：
10.1007/s00192-022-05120-w
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发表时间：
2022-06
影响因子：
1.8
通讯作者：
Hoyte, Lennox
中科院分区：
文献类型：
--
作者：
Egorov, Vladimir;van Raalte, Heather;Takacs, Peter;Shobeiri, S. Abbas;Lucente, Vincent;Hoyte, Lennox
关键词：
本研究的目的是开发和验证一个新的积分参数，生物力学完整性评分（BI评分），女性骨盆底的表征。多中心观察性病例对照研究共纳入253例正常和盆腔器官脱垂（POP）的受试者; 125例受试者的盆底状况正常，128例受试者的POP II期或更高。使用阴道触觉成像仪（VTI）采集并自动计算8个VTI测试程序（探头插入、抬高、旋转、Valsalva动作、两个平面中的随意肌肉收缩、放松和反射收缩）的52个生物力学参数。应用统计学方法（t检验，相关性）来确定VTI参数敏感的盆腔条件。26个参数被确定为在统计上对持久性有机污染物的发展具有敏感性。他们被分为五组，以表征（1）组织弹性，（2）骨盆支撑，（3）骨盆肌肉收缩，（4）不随意肌肉松弛，（5）骨盆肌肉活动度。将每个参数转换为与患者年龄相似的骨密度T评分的标准差单位。具有指定权重的线性组合导致组（1）-（5）的五个组分参数的组成和以标准差为单位的BI评分。POP与正常条件下BI评分的p值为p = 4.3 × 10−31。定义了正常骨盆底条件下BI评分相对于年龄的参考曲线。在未来的研究和实际应用中，可以用BI评分研究疾病条件下盆腔组织、支撑结构和功能的定量转化。
The aim of this study is to develop and validate a new integral parameter, the Biomechanical Integrity score (BI-score), for the characterization of the female pelvic floor. A total of 253 subjects with normal and pelvic organ prolapse (POP) conditions were included in the multi-site observational, case-control study; 125 subjects had normal pelvic floor conditions, and 128 subjects had POP stage II or higher. A Vaginal Tactile Imager (VTI) was used to acquire and automatically calculate 52 biomechanical parameters for eight VTI test procedures (probe insertion, elevation, rotation, Valsalva maneuver, voluntary muscle contractions in two planes, relaxation, and reflex contraction). Statistical methods were applied (t-test, correlation) to identify the VTI parameters sensitive to the pelvic conditions. Twenty-six parameters were identified as statistically sensitive to POP development. They were subdivided into five groups to characterize (1) tissue elasticity, (2) pelvic support, (3) pelvic muscle contraction, (4) involuntary muscle relaxation, and (5) pelvic muscle mobility. Every parameter was transformed to its standard deviation units against the patient age similar to T-score for bone density. Linear combinations with specified weights led to the composition of five component parameters for groups (1)–(5) and the BI-score in standard deviation units. The p-value for the BI-score has p = 4.3 × 10−31 for POP versus normal conditions. A reference BI-score curve against age for normal pelvic floor conditions was defined. Quantitative transformations of the pelvic tissues, support structures, and functions under diseased conditions may be studied with the BI-score in future research and practical applications.
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影响因子：
--
作者：
Silva, Ana Catarina A.;Maglinte, Dean D. T.
通讯作者：
Maglinte, Dean D. T.
DOI：
10.2147/ijwh.s136989
发表时间：
2017
期刊：
International journal of women's health
影响因子：
--
作者：
Lucente V;van Raalte H;Murphy M;Egorov V
通讯作者：
Egorov V
影响因子：
10.6
作者：
Egorov V;Sarvazyan AP
通讯作者：
Sarvazyan AP
影响因子：
1.8
作者：
MCGILL, R;TUKEY, JW;LARSEN, WA
通讯作者：
LARSEN, WA
影响因子：
2.4
作者：
Swamy, Nayanatara;Bajaj, Gitanjali;Ram, Roopa
通讯作者：
Ram, Roopa