Bridgehead enolates and bridgehead alkenes in a welwistatin model series
Bridgehead enolates and bridgehead alkenes in a welwistatin model series
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DOI：
10.1039/b820674k
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发表时间：
2009-01-01
影响因子：
4.9
通讯作者：
Lewis, William
中科院分区：
文献类型：
--
作者：
Boissel, Valerie;Simpkins, Nigel S.;Lewis, William
在具有韦氏他汀骨架的酮中可以存在桥头位，这有利于天然产物中存在的异硫氰酸酯官能团的安装，并且还能够合成显著的桥头位烯烃。
Bridgehead metallation is possible in a ketone having the welwistatin skeleton, and this facilitates installation of the isothiocyanate function present in the natural product, and also enables synthesis of remarkable bridgehead alkenes.