Single-sided device for magnetic particle imaging
Single-sided device for magnetic particle imaging
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DOI：
10.1088/0022-3727/42/2/022001
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发表时间：
2009-01-21
影响因子：
3.4
通讯作者：
Buzug, Thorsten M.
中科院分区：
文献类型：
--
作者：
Sattel, Timo F.;Knopp, Tobias;Buzug, Thorsten M.
最近，一种新的成像方式称为磁粒子成像（MPI）的介绍。该方法能够利用超顺磁性纳米颗粒的非线性磁化曲线，以高灵敏度、高分辨率和高成像速度对超顺磁性纳米颗粒的分布进行成像。到目前为止，所有已发表的模拟以及实验工作都使用扫描仪设置，其中视场（FOV）位于对称线圈配置之间。然而，这对标本造成了尺寸限制。在本文中，我们提出了一种新的，所谓的单面扫描仪，这是适用于感兴趣的对象，只是从一个方面的可行性研究。因此，将样本装入扫描仪的问题不再存在，这表明MPI迈出了重要一步。迄今为止，单侧器械的FOV仅限于一维。第一个实验结果的成像幻影含有超顺磁性流体显示分辨率高达1毫米，确实是有前途的。
Recently, a new imaging modality called magnetic particle imaging (MPI) was introduced. The method is capable of imaging the distribution of superparamagnetic nanoparticles at high sensitivity, high resolution and high imaging speed by exploiting their non-linear magnetization curve. Up to now, all published simulation as well as experimental work uses a scanner setup, where the field of view (FOV) lies in between a symmetric coil configuration. This, however, poses a size limitation for the specimens. In this paper, we present a feasibility study of a new, so-called single-sided scanner, which is applied to the object of interest merely from one side. Thus, the problem of the specimen fitting into the scanner no longer exists, which denotes a major step for MPI. To date, the FOV of the single-sided device is limited to one dimension. First experimental results on imaging phantoms containing a superparamagnetic fluid show a resolution of up to 1mm and are indeed promising.