The influence of the cyclopeptide sequence on its coordination abilities towards Cu(II)
The influence of the cyclopeptide sequence on its coordination abilities towards Cu(II)
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DOI：
10.1016/j.poly.2010.01.029
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发表时间：
2010-04-19
期刊：
影响因子：
2.6
通讯作者：
Oldziej, Stanislaw
中科院分区：
文献类型：
--
作者：
Brasun, Justyna;Matera-Witkiewicz, Agnieszka;Oldziej, Stanislaw
介绍了三种新型环六肽与三个组氨酸残基的结合能力。电位和光谱分析结果，结合理论计算，可以表征c(GlyHisArgHisHisGly), c(GlyHisArgHisGlyHis), c（GlyHisArgGlyHisHis）对铜（II）离子的配位能力，以及肽序列对铜（II）结合效率的影响，并给出了形成配合物的类型。(C) 2010 Elsevier Ltd.版权所有。
The binding abilities of three novel cyclohexapeptides with three histidyl residues are presented. The analysis of the potentiometric and spectroscopic results, together with the theoretical calculations, allow the characterization of the coordination abilities of c(GlyHisArgHisHisGly), c(GlyHisArgHisGlyHis), c(GlyHisArgGlyHisHis) towards copper(II) ions and the impact of the peptide sequence on the efficiency in Cu(II) binding, and the type of formed complexes is also presented. (C) 2010 Elsevier Ltd. All rights reserved.