Continuous monitoring of left ventricular function by an ambulatory radionuclide detector in patients with coronary artery disease.

Continuous monitoring of left ventricular function by an ambulatory radionuclide detector in patients with coronary artery disease.
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通过流动放射性核素检测仪连续监测冠状动脉疾病患者的左心室功能。

DOI:
10.1016/s0735-1097(88)80054-8
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发表时间:
1988
影响因子:
24
通讯作者:
Strauss,HW
Strauss,HW
中科院分区:
医学1区
文献类型:
--
作者:
Tamaki,N;Yasuda,T;Moore,RH;Gill,JB;Boucher,CA;HutterJr,AM;Gold,HK;Strauss,HW

文献摘要

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应用放射性核素记录仪连续监测12例正常人和39例冠心病患者在各种日常活动时的左室整体功能和改良V5导联心电图。动态研究显示,在水平表面上行走导致12名正常受试者中的11名和32名患者中的18名左心室射血分数增加> 6%单位,在16例冠心病患者中观察到36次(6 - 18%)持续≥ 1 min; 12次发作伴有胸痛或呼吸急促,24次无症状。心电图ST段压低提示缺血记录在6的12个症状和5的24个无症状发作。在10的12个症状发作,左心室射血分数开始下降30至90秒前的症状onse.These研究表明,连续监测左心室功能和心电图可能允许分层的ST段压低事件提示缺血的程度左心室功能障碍,他们生产。
Global left ventricular function and a modified V5electrocardiographic (ECG) lead were continuously monitored by a radionuclide recorder in 12 normal subjects and 39 patients with coronary artery disease while the subjects were performing various daily activities. The ambulatory studies revealed that walking on a level surface caused 11 of 12 normal subjects and 18 of 32 patients to increase their left ventricular ejection fraction by >6% units.A transient decrease in left ventricular ejection fraction (6 to 18 %) lasting ≥1 min was observed on 36 occasions in 16 patients with coronary artery disease; 12 episodes were accompanied by chest pain or shortness of breath and 24 were asymptomatic. Electrocardiographic ST segment depression suggestive of ischemia was recorded in 6 of the 12 symptomatic and 5 of the 24 asymptomatic episodes. In 10 of the 12 symptomatic episodes, left ventricular ejection fraction began to decrease 30 to 90 s before the onset of symptoms.These studies suggest that continuous monitoring of both left ventricular function and the ECG may permit stratification of episodes of ST depression suggesting ischemia by the degree of left ventricular dysfunction they produce.