Continuous monitoring of left ventricular function by an ambulatory radionuclide detector in patients with coronary artery disease.
Continuous monitoring of left ventricular function by an ambulatory radionuclide detector in patients with coronary artery disease.
复制标题
通过流动放射性核素检测仪连续监测冠状动脉疾病患者的左心室功能。
DOI:
10.1016/s0735-1097(88)80054-8
复制
发表时间:
1988
影响因子:
24
通讯作者:
Strauss,HW
中科院分区:
文献类型:
--
作者:
Tamaki,N;Yasuda,T;Moore,RH;Gill,JB;Boucher,CA;HutterJr,AM;Gold,HK;Strauss,HW
Global left ventricular function and a modified V5electrocardiographic (ECG) lead were continuously monitored by a radionuclide recorder in 12 normal subjects and 39 patients with coronary artery disease while the subjects were performing various daily activities. The ambulatory studies revealed that walking on a level surface caused 11 of 12 normal subjects and 18 of 32 patients to increase their left ventricular ejection fraction by >6% units.A transient decrease in left ventricular ejection fraction (6 to 18 %) lasting ≥1 min was observed on 36 occasions in 16 patients with coronary artery disease; 12 episodes were accompanied by chest pain or shortness of breath and 24 were asymptomatic. Electrocardiographic ST segment depression suggestive of ischemia was recorded in 6 of the 12 symptomatic and 5 of the 24 asymptomatic episodes. In 10 of the 12 symptomatic episodes, left ventricular ejection fraction began to decrease 30 to 90 s before the onset of symptoms.These studies suggest that continuous monitoring of both left ventricular function and the ECG may permit stratification of episodes of ST depression suggesting ischemia by the degree of left ventricular dysfunction they produce.