Significant reduction of methicillin-resistant Staphylococcus aureus bacteremia in geriatric wards after introduction of infection control measures against nosocomial infections.
Significant reduction of methicillin-resistant Staphylococcus aureus bacteremia in geriatric wards after introduction of infection control measures against nosocomial infections.
复制标题
引入针对医院感染的感染控制措施后，老年病房的耐甲氧西林金黄色葡萄球菌菌血症显着减少。
作者：
H. Masaki;H. Watanabe;S. Degawa;H. Yoshimine;N. Asoh;N. Rikitomi;K. Matsumoto;K. Ahmed;Kiwao Watanabe;Kazunori Oishi;T. Nagatake
目标
(1)探讨老年病房耐甲氧西林金黄色葡萄球菌(MRSA)菌血症感染控制措施的效果。 (2) 确定MRSA菌血症的诱发危险因素。
方法
对1991年1月至1995年3月发生的院内菌血症病例进行回顾性分析。研究期间分为4个年度时段，并以1991年1月至12月第1时段作为对照。
材料
我们对长崎大学附属爱野纪念医院老年病房（190张床位）的院内菌血症患者进行了调查。
结果
引入严格的感染控制和预防计划后，观察到 MRSA 引起的院内菌血症病例显着减少（第 1 期与第 2、3 和 4 期：分别为 p<0.00833、p<0.00167 和 p<0.00167）。菌血症的主要来源包括尿路感染、静脉导管相关感染和感染性褥疮。褥疮溃疡的改善与 MRSA 菌血症的显着减少相关（第 1 期与第 2 期和第 3 期相比：p<0.00017 和 p<0.00833）。
结论
老年病房需要采取严格的感染控制计划，包括预防和治疗褥疮，以减少和预防 MRSA 菌血症。
OBJECTIVES
(1) To investigate the efficacy of infection control measures against methicillin-resistant Staphylococcus aureus (MRSA) bacteremias in geriatric wards. (2) To identify predisposing risk factors for MRSA bacteremia.
METHODS
Cases with nosocomial bacteremias were retrospectively analyzed between January 1991 and March 1995. The study period was divided into four annual periods and the period 1, January to December 1991, was applied as the control.
MATERIALS
We investigated patients with nosocomial bacteremias in geriatric wards (190 beds) of AINO Memorial Hospital, affiliated with Nagasaki University.
RESULTS
A significant reduction in cases with MRSA-induced nosocomial bacteremia was observed after the introduction of a stringent infection control and prevention program (period 1 vs. periods 2, 3, and 4: p<0.00833, p<0.00167, and p<0.00167, respectively). The major source of bacteremia included urinary tract infections, intravenous catheter-related infections, and infected decubitus ulcers. Improvement of decubitus ulcer was associated with a significant reduction in MRSA bacteremia (period 1 vs. periods 2 and 3: p<0.00017 and p<0.00833).
CONCLUSION
Stringent infection control programs, including prevention and treatment of decubitus ulcers, are necessary in geriatric wards to reduce and prevent MRSA bacteremia.
耐甲氧西林金黄色葡萄球菌引起的医院感染的流行病学。
影响因子：
39.2
作者：
Thompson,RL;Cabezudo,I;Wenzel,RP
通讯作者：
Wenzel,RP