Pseudopyronines A and B, α-pyrones produced by a marine Pseudomonas sp F92S91, and evidence for the conversion of 4-hydroxy-α-pyrone to 3-furanone
Pseudopyronines A and B, α-pyrones produced by a marine Pseudomonas sp F92S91, and evidence for the conversion of 4-hydroxy-α-pyrone to 3-furanone
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DOI：
10.1021/np050038v
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发表时间：
2005-06-01
影响因子：
5.1
通讯作者：
Carter, GT
中科院分区：
文献类型：
--
作者：
Kong, FM;Singh, MP;Carter, GT
在我们寻找细菌脂肪酸生物合成抑制剂的过程中，从海洋假单胞菌中分离出了两种新的 α-吡喃酮：假吡喃宁 A (1) 和 B (2)。 F92S91。天然存在的 α-吡喃酮似乎不稳定，假吡喃宁 B 转化为氧化产物 3-呋喃酮 (3) 即可证明这一点。通过包括 2D-NMR 数据的光谱分析进行结构阐明。
In our search for inhibitors of bacterial fatty acid biosynthesis, two new alpha-pyrones, pseudopyronines A (1) and B (2), were isolated from a marine Pseudomonas sp. F92S91. The naturally occurring a-pyrones appeared to be unstable, evidenced by the conversion of pseudopyronine B into an oxidation product, 3-furanone (3). Structural elucidations were made by spectroscopic analyses including 2D-NMR data.