In vivo real-time intravascular MRI.
In vivo real-time intravascular MRI.
复制标题
体内实时血管内 MRI。
DOI：
10.1081/jcmr-120003948
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Hu,BobS
中科院分区：
文献类型：
--
作者：
Rivas,PedroA;Nayak,KrishnaS;Scott,GreigC;McConnell,MichaelV;Kerr,AdamB;Nishimura,DwightG;Pauly,JohnM;Hu,BobS
目的。磁共振成像（MRI）是一种基于导管的成像和干预的新兴技术。实时 MRI 是克服血管内成像导管和生理运动的有前途的方法。方法。所有成像均在具有高速梯度的 1.5 T Signa MRI 扫描仪上进行。设计和构建了多个导管线圈，包括薄型、短截线匹配线圈。比较了线圈灵敏度模式和 SNR 测量结果。使用专用工作站以交错螺旋序列进行实时成像，提供实时数据采集、图像重建以及交互式控制和显示。通过结合片外饱和脉冲实现了实时“黑血”成像。成像序列在连续流模型中进行测试，然后使用 2 mm 导管线圈在兔主动脉中进行体内测试。结果。实时血管内成像序列以高达每秒 16 帧的速度实现了 120-440 微米的分辨率。薄型短截线调谐导管线圈实现了与较大的传统线圈设计相似的信噪比。在体模实验中，添加实时黑血饱和脉冲有效地抑制了血流信号，并实现了体模墙的可视化。体内实验清楚地显示了兔主动脉壁的实时血管内成像，具有最小的运动伪影和有效的血液信号抑制。结论。采用薄型线圈设计的实时成像显着增强了血管内 MRI。
Purpose. The Magnetic resonance imaging (MRI) is an emerging technology for catheter-based imaging and interventions. Real-time MRI is a promising method for overcoming catheter and physiologic motion for intravascular imaging.Methods. All imaging was performed on a 1.5 T Signa MRI scanner with high-speed gradients. Multiple catheter coils were designed and constructed, including low-profile, stub-matched coils. Coil sensitivity patterns and SNR measurements were compared. Real-time imaging was performed with an interleaved spiral sequence using a dedicated workstation, providing real-time data acquisition, image reconstruction and interactive control and display. Real-time “black-blood” imaging was achieved through incorporation of off-slice saturation pulses. The imaging sequence was tested in a continuous flow phantom and then in vivo in the rabbit aorta using a 2 mm catheter coil.Results. The real-time intravascular imaging sequence achieved 120–440 micron resolution at up to 16 frames per second. Low-profile stub-tuned catheter coils achieved similar SNR to larger traditional coil designs. In the phantom experiments, addition of real-time black-blood saturation pulses effectively suppressed the flow signal and allowed visualization of the phantom wall. In vivo experiments clearly showed real-time intravascular imaging of the rabbit aortic wall with minimal motion artifacts and effective blood signal suppression.Conclusions. Real-time imaging with low-profile coil designs provides significant enhancements to intravascular MRI.