Long-term treatment and suicidal behavior in severe depression:: ECT and antidepressant pharmacotherapy may have different effects on the occurrence and seriousness of suicide attempts

Long-term treatment and suicidal behavior in severe depression:: ECT and antidepressant pharmacotherapy may have different effects on the occurrence and seriousness of suicide attempts
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DOI:
10.1002/da.20134
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发表时间:
2006-01-01
影响因子:
7.4
通讯作者:
Berglund, M
Berglund, M
中科院分区:
医学1区
文献类型:
--
作者:
Brådvik, L;Berglund, M

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在这篇文章中,我们的目的是评估长期治疗抑郁发作与在指数入院时有严重抑郁的患者企图或完全自杀之间的关系。对96名患有原发性重度抑郁症的自杀者和匹配的对照组进行了盲法记录评估。在这些人中,分别有57人和33人试图自杀。在电休克治疗(ECT)后,尝试的发生较少见。然而,与没有接受治疗和ECT相比,服用至少4周抗抑郁药物的患者自杀企图的严重性似乎有所降低。自杀综合征与抑郁无关的理论似乎得到了支持。建议在ECT后继续治疗。
Our objective in this article is to assess the relation between long-term treatments of depressive episodes and attempted or completed suicide in patients who had had a severe depression at index admission. A blind record evaluation of 96 suicides with a primary severe depression and matched controls has been performed. Out of those, 57 and 33, respectively, bad made suicide attempts. Occurrence of attempt was less common after electroconvulsive therapy (ECT). However, seriousness of suicide attempt appeared to be reduced in those with at least 4 weeks of antidepressant medication compared to no treatment and ECT The theory of a suicidal syndrome independent of depression seems supported. Continuation treatment after ECT is recommended.