Patterns of senescence in human cardiovascular fitness: VO2 max in subsistence and industrialized populations.
Patterns of senescence in human cardiovascular fitness: VO2 max in subsistence and industrialized populations.
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DOI：
10.1002/ajhb.22445
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发表时间：
2013-11-01
期刊：
影响因子：
--
通讯作者：
Yetish, Gandhi
中科院分区：
文献类型：
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作者：
Pisor, Anne C;Gurven, Michael;Yetish, Gandhi
目的：这项研究探讨了心血管健康水平和衰老下降是否在玻利维亚和加拿大的Tsimane，以及其他生存和工业化人口相似。在Tsimane中，我们研究了发病率是否预示着心血管健康水平较低和下降较快，或者他们的生活方式（例如，高体力活动）促进高水平和缓慢下降。或者，高活动水平和发病率可能会抵消，使Tsimane健身水平和下降是类似于那些在industrialized population.METHODS：最大摄氧量（VO 2最大）估计使用台阶试验心率方法为701名参与者。我们将这些估计与加拿大健康措施调查和以前在工业化和自给人口中的研究进行了比较。我们评估了是否健康指标和代理市场一体化与VO 2最大水平和下降率为Tsimane.RESULTS：Tsimane有显着较高的水平VO 2最大和下降速度比加拿大人慢;初步证据表明，VO 2最大水平之间的差异其他生存和工业化人口。低血红蛋白预测低VO 2最大Tsimane女性，而蠕虫感染预测高VO 2最大Tsimane男性，虽然结果可能是特定的VO 2最大缩放参数使用。没有变量测试交互与年龄适度declination.CONCLUSIONS：Tsimane表现出较高水平的心血管健康比工业化人口，但水平类似于其他生存人口。Tsimane的高VO 2 max与他们的高体力活动和在以前的研究中测量的心血管疾病指标相一致。
OBJECTIVES: This study explores whether cardiovascular fitness levels and senescent decline are similar in the Tsimane of Bolivia and Canadians, as well as other subsistence and industrialized populations. Among Tsimane, we examine whether morbidity predicts lower levels and faster decline of cardiovascular fitness, or whether their lifestyle (e.g., high physical activity) promotes high levels and slow decline. Alternatively, high activity levels and morbidity might counterbalance such that Tsimane fitness levels and decline are similar to those in industrialized populations.METHODS: Maximal oxygen uptake (VO2 max) was estimated using a step test heart rate method for 701 participants. We compared these estimates to the Canadian Health Measures Survey and previous studies in industrialized and subsistence populations. We evaluated whether health indicators and proxies for market integration were associated with VO2 max levels and rate of decline for the Tsimane.RESULTS: The Tsimane have significantly higher levels of VO2 max and slower rates of decline than Canadians; initial evidence suggests differences in VO2 max levels between other subsistence and industrialized populations. Low hemoglobin predicts low VO2 max for Tsimane women while helminth infection predicts high VO2 max for Tsimane men, though results might be specific to the VO2 max scaling parameter used. No variables tested interact with age to moderate decline.CONCLUSIONS: The Tsimane demonstrate higher levels of cardiovascular fitness than industrialized populations, but levels similar to other subsistence populations. The high VO2 max of Tsimane is consistent with their high physical activity and few indicators of cardiovascular disease, measured in previous studies.