Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behcet's Disease
Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behcet's Disease
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DOI：
10.1080/08820538.2016.1178310
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发表时间：
2017-01-01
影响因子：
1.7
通讯作者：
Modjtahedi, Bobeck S.
中科院分区：
文献类型：
--
作者：
Bazvand, Fatemeh;Zarei, Mohammad;Modjtahedi, Bobeck S.
目的：评价白塞病患者的眼部表现和眼底荧光素血管造影（FA）的表现，以及视力与血管造影的关系。方法：回顾性分析法拉比眼科医院收治的白塞氏病患者。结果：纳入患者46例（92眼），平均年龄33.41±10.67岁。最常见的症状和体征分别是视力下降（76%）和葡萄膜炎（87%）。全葡萄膜炎是最常见的葡萄膜炎类型（76%）。在FA患者中，血管炎是最常见的发现（87%），并且在视力低于20/200的患者中更为严重。FA患者黄斑渗漏（P = 0.001）、动脉狭窄（P = 0.000）和视网膜后血管炎（P = 0.002）均与最终视力恶化有关。结论：白塞病最常见的眼部表现是全葡萄膜炎和血管炎。血管炎、动脉狭窄和黄斑渗漏的位置可以预测初始FA的视力预后。
Purpose: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behcet's disease as well as the relationship between visual acuity and angiographic findings. Methods: Retrospective chart review of patients with Behcet's disease seen at the Farabi Eye Hospital. Results: Forty-six patients (92 eyes) with mean age of 33.41 +/- 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity. Conclusion: The most common ocular findings in Behcet's disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis.