Transition Metal-Free trans-Selective Alkynylboration of Alkynes
Transition Metal-Free trans-Selective Alkynylboration of Alkynes
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DOI：
10.1021/jacs.7b06212
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发表时间：
2017-09-13
影响因子：
15
通讯作者：
Uchiyama, Masanobu
中科院分区：
文献类型：
--
作者：
Nogami, Marina;Hirano, Keiichi;Uchiyama, Masanobu
我们报告了第一个无过渡金属和反式选择性炔烃的炔基硼化反应。这种前所未有的碳硼化反应是通过使用炔丙醇对炔基硼酸酯进行假分子内活化来实现的。碳硼化反应得到 4-炔基-1,2-氧杂硼醇-2(5H)-醇，它不仅是通用的结构单元，而且还表现出强烈的紫蓝色荧光发射。
We report the first transition metal-free and trans-selective alkynylboration reaction of alkynes. This unprecedented carboboration reaction is enabled by pseudo-intramolecular activation of alkynylboronates using propargylic alcohols. The carboboration affords 4-alkynyl-1,2-oxaborol-2(5H)-ols, which are not only versatile building blocks but also exhibit strong violet blue fluorescence emission.