Surgical results for hepatocellular carcinoma with macroscopic portal vein tumor thrombosis
Surgical results for hepatocellular carcinoma with macroscopic portal vein tumor thrombosis
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DOI：
10.1016/s1072-7515(00)00740-7
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发表时间：
2000-12-01
影响因子：
5.2
通讯作者：
Kosuge, T
中科院分区：
文献类型：
--
作者：
Ohkubo, T;Yamamoto, J;Kosuge, T
背景资料：肝切除术后肝细胞癌与宏观门静脉癌栓的长期结果尚不清楚。研究设计：47例肝细胞癌患者的癌栓在节段性门静脉分支（n = 33）和第一门静脉分支或门静脉主干（n = 14）在这项研究中进行了审查。根据14个临床病理变量计算患者的生存率。结果：总的1年、3年和5年生存率分别为53.9%、33.2%和23.9%。预后良好的指标包括根治性肝切除，肿瘤直径小于10 cm，没有肝内转移.Conclusions：肝切除术应被视为一种治疗选择肝细胞癌与宏观门静脉癌栓时，肿瘤是小的，可以预期根治性肝切除术。（J Am科尔外科杂志2000;191：657-660。(C)2000年由美国外科医生学会出版）。
Background: The longterm results after liver resection for hepatocellular carcinoma with macroscopic tumor thrombus of the portal vein are unclear.Study Design: The records of 47 HCC patients with tumor thrombus in the segmental portal branch (n = 33) and the first portal branch or portal vein trunk (n = 14) were reviewed in this study. Survival rates of the patients were calculated with regard to 14 clinico-pathologic variables. A log-rank analysis was performed to identify which variables predicted the prognosis.Results: Overall 1-, 3-, and 5-year survival rates were 53.9%, 33.2%, and 23.9%, respectively. The indicators of a favorable prognosis included curative liver resection, tumor size less than 10 cm in diameter, and absence of intrahepatic metastases.Conclusions: Liver resection should be considered a therapeutic option for hepatocellular carcinoma with macroscopic portal vein tumor thrombus when the tumor is small and curative liver resection can be expected. (J Am Coll Surg 2000;191:657-660. (C) 2000 by the American College of Surgeons).