SOCIAL CONNECTIONS AND MORTALITY FROM ALL CAUSES AND FROM CARDIOVASCULAR-DISEASE - PROSPECTIVE EVIDENCE FROM EASTERN FINLAND
SOCIAL CONNECTIONS AND MORTALITY FROM ALL CAUSES AND FROM CARDIOVASCULAR-DISEASE - PROSPECTIVE EVIDENCE FROM EASTERN FINLAND
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DOI：
10.1093/oxfordjournals.aje.a114977
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发表时间：
1988-08-01
影响因子：
5
通讯作者：
PUSKA, P
中科院分区：
文献类型：
--
作者：
KAPLAN, GA;SALONEN, JT;PUSKA, P
社会关系的先验度量与各种原因、心血管疾病的五年死亡率（国际疾病分类）之间的关联。第八次修订（ICD-8）代码390-458)和缺血性心脏病（ICD-8代码410-414）是在1972年和1977年对芬兰东部的13,301名男性和女性进行的研究。对于男性来说，社会关系的广度和死亡率之间存在等级关联。在校正了年龄、吸烟、血清胆固醇、平均加权血压、流行疾病和其他可能混杂因素的多变量模型中，社会关系量表中处于最低两个五分位数的男性与处于最高五分位数的男性相比风险增加(优势比（OR）全因= 1.54,95%置信区间(CI) = 1.21-1.95；心血管疾病= 1.54,95% CI = 1.11-2.13；缺血性心脏病= 1.34,95% Cl = 0.94-1.90)。在女性中没有发现强烈或一致的关联。对于男性来说，这种联系会受到血压水平的影响，血压水平越高，社会关系越低的影响越大。在三个独立的分析中，没有证据表明在基线时由于流行疾病导致混淆或效果改变。
The association between an a priori measure of social connections and five-year mortality from all causes, cardiovascular disease (International Classification of Diseases. Eighth Revision (ICD-8) codes 390-458), and ishemic heart disease (ICD-8 codes 410-414) was studies in 13,301 men and women from eastern Finland who were interviewed in 1972 and 1977. For men there was a graded association between extent of social connections and mortality. In mulitvar models with adjustment for age, smoking, serum cholesterol, mean weighted blood pressure, of prevalent illness, and other possible confounders, men who were in the two lowest quintiles of the social connections scale were increased risk compared with those in the highest quintile (odds ratio (OR)all cause = 1.54, 95% confidence interval (CI) = 1.21-1.95; ORcardiovascular disease = 1.54, 95% CI = 1.11-2.13; ORischemic heart disease = 1.34, 95% Cl = 0.94-1.90). No strong or consistent association was found for women. The association for men was modified by levels of blood pressure with the effect of low social connections greater at higher levels of blood pressure. In the three separate analyses, there was no evidence for confounding or effect modification due to prevalent illness at baseline.