BIPOLAR CELLS IN MONKEY RETINA SELECTIVE FOR THE CONES LIKELY TO BE BLUE-SENSITIVE
BIPOLAR CELLS IN MONKEY RETINA SELECTIVE FOR THE CONES LIKELY TO BE BLUE-SENSITIVE
复制标题
DOI：
10.1038/308184a0
复制
发表时间：
1984-01-01
期刊：
影响因子：
64.8
通讯作者：
MARIANI, AP
中科院分区：
文献类型：
--
作者：
MARIANI, AP
双极细胞是一类视网膜中间神经元，其外丛状层中的树突与光感受器接触，轴突终止于内丛状层1，在那里它们传递神经节细胞的中心反应2,3。在猴子中，许多神经节细胞对三个不同视锥细胞 5、6 中每一个的刺激都有选择性地做出反应。视锥双极细胞有五种类型：扁平型和内陷型侏儒7-9；弥漫性、扁平性7和内陷性锥体7、10；和巨人，双层11。尽管猴子的许多神经节细胞对三种不同视锥细胞机制之一具有特异性，但已知没有一种双极细胞与硬骨鱼视网膜中不同光谱类型视锥细胞的形态学识别对应物连接12-15。然而，在这里，我描述了在恒河猴视网膜的高尔基体制备物中发现的双极细胞，该细胞显示出其树突与外丛状层中的锥蒂接触的明显选择性和图案化分布。树突接触的锥体间距及其分布与被认为对蓝色敏感的锥体的锥体间距和比例相匹配16,17。
Bipolar cells are a class of retinal interneurone with dendrites in the outer plexiform layer that contact photoreceptors, and axons terminating in the inner plexiform layer1where they convey the centre responses of ganglion cells2,3. In the monkey, many of whose ganglion cells respond to stimuli selective4for each of the three different cones5,6. There are five types of cone bipolar cells: flat and invaginating midget7–9; diffuse, flat7and invaginating cone7,10; and giant, bistratified11. Although many of the monkey's ganglion cells are specific for one of the three different cone mechanisms, none of the bipolar cells are known to connect to the morphologically identified counterparts of the different spectral types of cones as in teleost retina12–15. Here, however, I describe a bipolar cell found in Golgi preparations of the rhesus monkey retina which displays an apparently selective and patterned distribution of its dendritic contacts with cone pedicles in the outer plexiform layer. The intercone spacing of dendritic contacts and their distribution match the intercone spacing and proportion of cones thought to be blue-sensitive16,17.