MITOPRED: a web server for the prediction of mitochondrial proteins
MITOPRED: a web server for the prediction of mitochondrial proteins
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DOI：
10.1093/nar/gkh374
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发表时间：
2004-07-01
影响因子：
14.9
通讯作者：
Subramaniam, S
中科院分区：
文献类型：
--
作者：
Guda, C;Guda, P;Subramaniam, S
MITOPRED网络服务器可以预测所有真核生物物种中的核编码线粒体蛋白。预测使用一种新的算法，主要是基于Pfam结构域发生模式的线粒体和非线粒体的位置。预先计算的预测可以立即访问酿酒酵母、秀丽隐杆线虫、果蝇、智人、小家鼠和拟南芥物种的蛋白质组以及Swiss-Prot和TrEMBL数据库中的所有真核生物序列。在不同的置信水平下，可以通过四个不同的选项进行验证：（i）输入Swiss-Prot/TrEMBL登录号;（ii）上传具有这些登录号的本地文件;（iii）输入蛋白质序列;（iv）上传包含FASTA格式的蛋白质序列的本地文件。为预先计算的预测数据库安排自动更新，以便提供对最新数据的访问。服务器、其文档和数据可从http://mitopred.sdsc.edu获得。
MITOPRED web server enables prediction of nucleus-encoded mitochondrial proteins in all eukaryotic species. Predictions are made using a new algorithm based primarily on Pfam domain occurrence patterns in mitochondrial and non-mitochondrial locations. Pre-calculated predictions are instantly accessible for proteomes of Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila, Homo sapiens, Mus musculus and Arabidopsis species as well as all the eukaryotic sequences in the Swiss-Prot and TrEMBL databases. Queries, at different confidence levels, can be made through four distinct options: (i) entering Swiss-Prot/TrEMBL accession numbers; (ii) uploading a local file with such accession numbers; (iii) entering protein sequences; (iv) uploading a local file containing protein sequences in FASTA format. Automated updates are scheduled for the pre-calculated prediction database so as to provide access to the most current data. The server, its documentation and the data are available from http://mitopred.sdsc.edu.