Exploring the Association Between Depression and Social and Biobehavioral HIV Risk Factors Among Female Sex Workers in Nelson Mandela Bay Municipality, South Africa.

Exploring the Association Between Depression and Social and Biobehavioral HIV Risk Factors Among Female Sex Workers in Nelson Mandela Bay Municipality, South Africa.
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探索南非纳尔逊·曼德拉湾市女性性工作者抑郁症与社会和生物行为艾滋病毒危险因素之间的关联。

DOI:
10.1089/aid.2020.0233
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发表时间:
2021
影响因子:
1.5
通讯作者:
Baral,Stefan
Baral,Stefan
中科院分区:
医学4区
文献类型:
--
作者:
Rossouw,Johannes;Schwartz,Sheree;Rao,Amrita;Mcingana,Mfezi;Young,Katherine;Hausler,Harry;Baral,Stefan

文献摘要

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本研究的目的是估计抑郁症的患病率女性性工作者(FSW)在城市沿海城市在南非,并探讨抑郁症和HIV相关的社会和生物行为的决定因素之间的关系。对FSW(n= 410)进行了一项横断面响应驱动抽样研究,包括社会行为问卷、基于PHQ-9(患者健康问卷-9)的抑郁症评估以及HIV和梅毒的生物学检测。样本中HIV感染率为64.1%。抑郁症的估计患病率为28.8%。抑郁症与社会脆弱性相关,如独居[调整后的患病率为1.82,95%置信区间(CI)为1.15-2.90]和食物不安全(aPR为2.19,95% CI为1.42-3.38)。梅毒检测结果阳性(aPR 1.46,95% CI 1.02-2.09)和自我报告的性传播疾病症状(aPR 1.78,95% CI 1.29-2.46)与抑郁症相关,但自我报告的安全套使用和HIV状态与抑郁症无关。FSW也不太可能向卫生保健提供者透露他们的职业状况(aPR 0.61,95% CI 0.42-0.89)或在过去12个月内接受性传播感染筛查(aPR 0.64,95% CI 0.43-0.95)。结果表明,抑郁症的患病率是高的FSW和抑郁症状与社会协变量和生物行为的HIV危险因素。
The aim of this study was to estimate the prevalence of depression among female sex workers (FSW) in an urban coastal city in South Africa, and to explore the relationship between depression and HIV-related social and biobehavioral determinants. A cross-sectional respondent-driven sampling study was conducted with FSW (n= 410), including a sociobehavioral questionnaire, PHQ-9 (Patient Health Questionnaire-9) based assessment of depression, and biological testing for HIV and syphilis. The prevalence of HIV in the sample was 64.1%. The estimated prevalence of depression was 28.8%. Depression was associated with social vulnerability such as living alone [adjusted prevalence ratio 1.82, 95% confidence interval (CI) 1.15–2.90] and food insecurity (aPR 2.19, 95% CI 1.42–3.38). A positive syphilis test result (aPR 1.46, 95% CI 1.02–2.09) and self-reported sexually transmitted disease symptoms (aPR 1.78, 95% CI 1.29–2.46) was associated with depression, but self-reported condom use and HIV status was not. FSW were also less likely to disclose their occupational status to health care providers (aPR 0.61, 95% CI 0.42–0.89) or undergo sexually transmitted infection screening in the last 12 months if they are depressed (aPR 0.64, 95% CI 0.43–0.95). The results demonstrate that the prevalence of depression is high among FSW and that depressive symptoms are associated with social covariates and biobehavioral HIV risk factors.